Abstract
Ageing is a universal but complex biological process, characterised by an impairment of bioenergetic function, a decreased ability to respond to stress, and an increased risk of age-associated diseases. In this article, we review the role of mitochondria in the human ageing process from the point of view of the well-documented decline in respiratory function and the increase in mutation and oxidative damage to the mitochondrial DNA of ageing tissues.
| Original language | English |
|---|---|
| Pages (from-to) | 8-13 |
| Number of pages | 6 |
| Journal | Bio Tech International |
| Volume | 17 |
| Issue number | 3 |
| State | Published - 06 2005 |
| Externally published | Yes |