Theoretical analysis of a continuous bioreactor subject to cyclic feed concentration

Sheng Chi Wu, Chia Chang Lin, Hwai Shen Liu*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

2 Scopus citations

Abstract

Continuous bioreactors operated periodically are theoretically compared with conventional steady state operations in terms of biomass production with various growth models. Analysis indicates that a continuous bioreactor subject to cyclic feed concentration may behave very differently from that by cyclic dilution rate. A bioreactor of Moser kinetics with constant yield factor, constant maintenance coefficient, or variable yield factor could perform better by periodic feed operation compared with that by optimal steady state operation. However, kinetic models of Monod, Tessier and Andrew could only result in superior performance with a variable yield factor. Therefore, the difference between Moser model and others is noticed.

Original languageEnglish
Pages (from-to)151-160
Number of pages10
JournalJournal of the Chinese Institute of Chemical Engineers
Volume30
Issue number2
StatePublished - 03 1999
Externally publishedYes

Keywords

  • Continuous bioreactor
  • Growth kinetic model
  • Optimal steady state operation
  • Periodic operation

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