Abstract
This study explores the potential of Au-Ag bimetallic alloy nanoparticles for LSPR-based biosensors. We present a theoretical framework that models analyte attachment to nanoparticles by considering the evolution of the analyte's refractive index relative to its concentration. Using glucose as a benchmark analyte, we calculate its refractive index and assess the performance of LSPR biosensors with varying molar fractions of Au-Ag alloys. Our findings demonstrate that Au-Ag alloy nanoparticles offer enhanced LSPR intensity and tunable chemical stability due to the molar fraction of Au, with the ability to precisely adjust the LSPR wavelength by modifying the alloy composition. This tunability provides significant advantages in sensitivity and specificity, advancing the application of Au-Ag alloy nanoparticles in biosensing technologies.
| Original language | English |
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| Title of host publication | 2024 IEEE Sensors, SENSORS 2024 - Conference Proceedings |
| Publisher | Institute of Electrical and Electronics Engineers Inc. |
| ISBN (Electronic) | 9798350363517 |
| DOIs | |
| State | Published - 2024 |
| Event | 2024 IEEE Sensors, SENSORS 2024 - Kobe, Japan Duration: 20 10 2024 → 23 10 2024 |
Publication series
| Name | Proceedings of IEEE Sensors |
|---|---|
| ISSN (Print) | 1930-0395 |
| ISSN (Electronic) | 2168-9229 |
Conference
| Conference | 2024 IEEE Sensors, SENSORS 2024 |
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| Country/Territory | Japan |
| City | Kobe |
| Period | 20/10/24 → 23/10/24 |
Bibliographical note
Publisher Copyright:© 2024 IEEE.
Keywords
- Au-Ag bimetallic alloys
- LSPR biosensor modeling
- analyte modeling
- nanoparticle