Thermosensitivity of dorsal raphe neurons in vitro

C. Larry Keenan; Nai Shin Chu

doi:10.1016/S0006-8993(87)80045-8

Thermosensitivity of dorsal raphe neurons in vitro

C. Larry Keenan^*
, Nai Shin Chu

^*Corresponding author for this work

University of California at Irvine

Research output: Contribution to journal › Journal Article › peer-review

8 Scopus citations

Abstract

Thermosensitivity of raphe neurons was studied in tissue slices of rat brainstems (400-500 μm). Measurement of activity of single cells in the dorsal raphe region of the slices revealed that the majority of neurons (89%) were sensitive to changes in temperature. Over the range 34 to 42 °C, 3 classes of thermosensitive cells were found: warm (61%), cold (15%) and biphasic type cells (13%). Many dorsal raphe neurons may be intrinsically temperature sensitive and may serve as extrahypothalamic thermodetector components in the integrative process of central thermoregulation.

Original language	English
Pages (from-to)	189-194
Number of pages	6
Journal	Brain Research
Volume	410
Issue number	1
DOIs	https://doi.org/10.1016/S0006-8993(87)80045-8
State	Published - 28 04 1987
Externally published	Yes

Keywords

Brainstem
Dorsal raphe
Thermoregulation

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10.1016/S0006-8993(87)80045-8

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title = "Thermosensitivity of dorsal raphe neurons in vitro",

abstract = "Thermosensitivity of raphe neurons was studied in tissue slices of rat brainstems (400-500 μm). Measurement of activity of single cells in the dorsal raphe region of the slices revealed that the majority of neurons (89\%) were sensitive to changes in temperature. Over the range 34 to 42 °C, 3 classes of thermosensitive cells were found: warm (61\%), cold (15\%) and biphasic type cells (13\%). Many dorsal raphe neurons may be intrinsically temperature sensitive and may serve as extrahypothalamic thermodetector components in the integrative process of central thermoregulation.",

keywords = "Brainstem, Dorsal raphe, Thermoregulation",

author = "Keenan, \{C. Larry\} and Chu, \{Nai Shin\}",

year = "1987",

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AU - Keenan, C. Larry

AU - Chu, Nai Shin

PY - 1987/4/28

Y1 - 1987/4/28

N2 - Thermosensitivity of raphe neurons was studied in tissue slices of rat brainstems (400-500 μm). Measurement of activity of single cells in the dorsal raphe region of the slices revealed that the majority of neurons (89%) were sensitive to changes in temperature. Over the range 34 to 42 °C, 3 classes of thermosensitive cells were found: warm (61%), cold (15%) and biphasic type cells (13%). Many dorsal raphe neurons may be intrinsically temperature sensitive and may serve as extrahypothalamic thermodetector components in the integrative process of central thermoregulation.

AB - Thermosensitivity of raphe neurons was studied in tissue slices of rat brainstems (400-500 μm). Measurement of activity of single cells in the dorsal raphe region of the slices revealed that the majority of neurons (89%) were sensitive to changes in temperature. Over the range 34 to 42 °C, 3 classes of thermosensitive cells were found: warm (61%), cold (15%) and biphasic type cells (13%). Many dorsal raphe neurons may be intrinsically temperature sensitive and may serve as extrahypothalamic thermodetector components in the integrative process of central thermoregulation.

KW - Brainstem

KW - Dorsal raphe

KW - Thermoregulation

UR - https://www.scopus.com/pages/publications/0023217854

U2 - 10.1016/S0006-8993(87)80045-8

DO - 10.1016/S0006-8993(87)80045-8

M3 - 文章

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AN - SCOPUS:0023217854

SN - 0006-8993

VL - 410

SP - 189

EP - 194

JO - Brain Research

JF - Brain Research

IS - 1

ER -

Thermosensitivity of dorsal raphe neurons in vitro

Abstract

Keywords

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