TP53 State Dictates Genome Stability, Clinical Presentation and Outcomes in Myelodysplastic Syndromes

Elsa Bernard; Yasuhito Nannya; Tetsuichi Yoshizato; Robert P. Hasserjian; Ryunosuke Saiki; Yusuke Shiozawa; Sean M. Devlin; Heinz Tuechler; Araxe Sarian; Luca Malcovati; Francesc Sole; Detlef Haase; Maria Creignou; Max Levine; Ulrich Germing; Catherine Cargo; Yanming Zhang; Juan Medina; Juan E. Arango Ossa; Julie Schanz; Arjan van de Loosdrecht; Martin Jadersten; John M. Bennett; Magnus Tobiasson; Olivier Kosmider; Matilde Y. Follo; Felicitas Thol; Ronald F. Pinheiro; Valeria Santini; Ioannis Kotsianidis; Jacqueline Boultwood; Fabio P. S. Santos; Senji Kasahara; Takayuki Ishikawa; Hisashi Tsurumi; Takaori-Kondo Akifumi; Toru Kiguchi; Chantana Polprasert; Virginia M. Klimek; Michael R. Savona; Monika Belickova; Christina Ganster; Lionel Ades; Matteo Giovanni Della Porta; Alexandra Smith; Yesenia Werner; Minal A. Patel; Agnes Viale; Katelynd Vanness; Donna S. Neuberg; Kristen E. Stevenson; Kamal Menghrajani; Kelly Bolton; Pierre Fenaux; Andrea Pellagatti; Uwe Platzbecker; Michael Heuser; Peter Valent; Shigeru Chiba; Yasushi Miyazaki; Carlo Finelli; Maria Teresa Voso; Lee-Yung Shih; Michaela Fontenay; Joop H. Jansen; Jose Cervera; Yoshiko Atsuta; Norbert Gattermann; Benjamin L. Ebert; Rafael Bejar; Peter L. Greenberg; Mario Cazzola; Eva Hellstrom Lindberg; Seishi Ogawa; Elli Papaemmanuil

doi:10.1182/blood-2019-129392

TP53 State Dictates Genome Stability, Clinical Presentation and Outcomes in Myelodysplastic Syndromes

Elsa Bernard, Yasuhito Nannya, Tetsuichi Yoshizato, Robert P. Hasserjian, Ryunosuke Saiki, Yusuke Shiozawa, Sean M. Devlin, Heinz Tuechler, Araxe Sarian, Luca Malcovati, Francesc Sole, Detlef Haase, Maria Creignou, Max Levine, Ulrich Germing, Catherine Cargo, Yanming Zhang, Juan Medina, Juan E. Arango Ossa, Julie SchanzArjan van de Loosdrecht, Martin Jadersten, John M. Bennett, Magnus Tobiasson, Olivier Kosmider, Matilde Y. Follo, Felicitas Thol, Ronald F. Pinheiro, Valeria Santini, Ioannis Kotsianidis, Jacqueline Boultwood, Fabio P. S. Santos, Senji Kasahara, Takayuki Ishikawa, Hisashi Tsurumi, Takaori-Kondo Akifumi, Toru Kiguchi, Chantana Polprasert, Virginia M. Klimek, Michael R. Savona, Monika Belickova, Christina Ganster, Lionel Ades, Matteo Giovanni Della Porta, Alexandra Smith, Yesenia Werner, Minal A. Patel, Agnes Viale, Katelynd Vanness, Donna S. Neuberg, Kristen E. Stevenson, Kamal Menghrajani, Kelly Bolton, Pierre Fenaux, Andrea Pellagatti, Uwe Platzbecker, Michael Heuser, Peter Valent, Shigeru Chiba, Yasushi Miyazaki, Carlo Finelli, Maria Teresa Voso, Lee-Yung Shih, Michaela Fontenay, Joop H. Jansen, Jose Cervera, Yoshiko Atsuta, Norbert Gattermann, Benjamin L. Ebert, Rafael Bejar, Peter L. Greenberg, Mario Cazzola, Eva Hellstrom Lindberg, Seishi Ogawa, Elli Papaemmanuil

School of Medicine

Research output: Contribution to journal › Journal Article › peer-review

Original language	American English
Journal	Blood
Volume	134
DOIs	https://doi.org/10.1182/blood-2019-129392
State	Published - 2019

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10.1182/blood-2019-129392

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Bernard, E., Nannya, Y., Yoshizato, T., Hasserjian, R. P., Saiki, R., Shiozawa, Y., Devlin, S. M., Tuechler, H., Sarian, A., Malcovati, L., Sole, F., Haase, D., Creignou, M., Levine, M., Germing, U., Cargo, C., Zhang, Y., Medina, J., Ossa, J. E. A., ... Papaemmanuil, E. (2019). TP53 State Dictates Genome Stability, Clinical Presentation and Outcomes in Myelodysplastic Syndromes. Blood, 134. https://doi.org/10.1182/blood-2019-129392

@article{130d217ba0ac45ddb1808b02dab8a4d8,

title = "TP53 State Dictates Genome Stability, Clinical Presentation and Outcomes in Myelodysplastic Syndromes",

author = "Elsa Bernard and Yasuhito Nannya and Tetsuichi Yoshizato and Hasserjian, {Robert P.} and Ryunosuke Saiki and Yusuke Shiozawa and Devlin, {Sean M.} and Heinz Tuechler and Araxe Sarian and Luca Malcovati and Francesc Sole and Detlef Haase and Maria Creignou and Max Levine and Ulrich Germing and Catherine Cargo and Yanming Zhang and Juan Medina and Ossa, {Juan E. Arango} and Julie Schanz and {van de Loosdrecht}, Arjan and Martin Jadersten and Bennett, {John M.} and Magnus Tobiasson and Olivier Kosmider and Follo, {Matilde Y.} and Felicitas Thol and Pinheiro, {Ronald F.} and Valeria Santini and Ioannis Kotsianidis and Jacqueline Boultwood and Santos, {Fabio P. S.} and Senji Kasahara and Takayuki Ishikawa and Hisashi Tsurumi and Takaori-Kondo Akifumi and Toru Kiguchi and Chantana Polprasert and Klimek, {Virginia M.} and Savona, {Michael R.} and Monika Belickova and Christina Ganster and Lionel Ades and {Della Porta}, {Matteo Giovanni} and Alexandra Smith and Yesenia Werner and Patel, {Minal A.} and Agnes Viale and Katelynd Vanness and Neuberg, {Donna S.} and Stevenson, {Kristen E.} and Kamal Menghrajani and Kelly Bolton and Pierre Fenaux and Andrea Pellagatti and Uwe Platzbecker and Michael Heuser and Peter Valent and Shigeru Chiba and Yasushi Miyazaki and Carlo Finelli and Voso, {Maria Teresa} and Lee-Yung Shih and Michaela Fontenay and Jansen, {Joop H.} and Jose Cervera and Yoshiko Atsuta and Norbert Gattermann and Ebert, {Benjamin L.} and Rafael Bejar and Greenberg, {Peter L.} and Mario Cazzola and Lindberg, {Eva Hellstrom} and Seishi Ogawa and Elli Papaemmanuil",

year = "2019",

doi = "10.1182/blood-2019-129392",

language = "American English",

volume = "134",

journal = "Blood",

issn = "0006-4971",

publisher = "Elsevier B.V.",

}

Bernard, E, Nannya, Y, Yoshizato, T, Hasserjian, RP, Saiki, R, Shiozawa, Y, Devlin, SM, Tuechler, H, Sarian, A, Malcovati, L, Sole, F, Haase, D, Creignou, M, Levine, M, Germing, U, Cargo, C, Zhang, Y, Medina, J, Ossa, JEA, Schanz, J, van de Loosdrecht, A, Jadersten, M, Bennett, JM, Tobiasson, M, Kosmider, O, Follo, MY, Thol, F, Pinheiro, RF, Santini, V, Kotsianidis, I, Boultwood, J, Santos, FPS, Kasahara, S, Ishikawa, T, Tsurumi, H, Akifumi, T-K, Kiguchi, T, Polprasert, C, Klimek, VM, Savona, MR, Belickova, M, Ganster, C, Ades, L, Della Porta, MG, Smith, A, Werner, Y, Patel, MA, Viale, A, Vanness, K, Neuberg, DS, Stevenson, KE, Menghrajani, K, Bolton, K, Fenaux, P, Pellagatti, A, Platzbecker, U, Heuser, M, Valent, P, Chiba, S, Miyazaki, Y, Finelli, C, Voso, MT, Shih, L-Y, Fontenay, M, Jansen, JH, Cervera, J, Atsuta, Y, Gattermann, N, Ebert, BL, Bejar, R, Greenberg, PL, Cazzola, M, Lindberg, EH, Ogawa, S & Papaemmanuil, E 2019, 'TP53 State Dictates Genome Stability, Clinical Presentation and Outcomes in Myelodysplastic Syndromes', Blood, vol. 134. https://doi.org/10.1182/blood-2019-129392

TY - JOUR

T1 - TP53 State Dictates Genome Stability, Clinical Presentation and Outcomes in Myelodysplastic Syndromes

AU - Bernard, Elsa

AU - Nannya, Yasuhito

AU - Yoshizato, Tetsuichi

AU - Hasserjian, Robert P.

AU - Saiki, Ryunosuke

AU - Shiozawa, Yusuke

AU - Devlin, Sean M.

AU - Tuechler, Heinz

AU - Sarian, Araxe

AU - Malcovati, Luca

AU - Sole, Francesc

AU - Haase, Detlef

AU - Creignou, Maria

AU - Levine, Max

AU - Germing, Ulrich

AU - Cargo, Catherine

AU - Zhang, Yanming

AU - Medina, Juan

AU - Ossa, Juan E. Arango

AU - Schanz, Julie

AU - van de Loosdrecht, Arjan

AU - Jadersten, Martin

AU - Bennett, John M.

AU - Tobiasson, Magnus

AU - Kosmider, Olivier

AU - Follo, Matilde Y.

AU - Thol, Felicitas

AU - Pinheiro, Ronald F.

AU - Santini, Valeria

AU - Kotsianidis, Ioannis

AU - Boultwood, Jacqueline

AU - Santos, Fabio P. S.

AU - Kasahara, Senji

AU - Ishikawa, Takayuki

AU - Tsurumi, Hisashi

AU - Akifumi, Takaori-Kondo

AU - Kiguchi, Toru

AU - Polprasert, Chantana

AU - Klimek, Virginia M.

AU - Savona, Michael R.

AU - Belickova, Monika

AU - Ganster, Christina

AU - Ades, Lionel

AU - Della Porta, Matteo Giovanni

AU - Smith, Alexandra

AU - Werner, Yesenia

AU - Patel, Minal A.

AU - Viale, Agnes

AU - Vanness, Katelynd

AU - Neuberg, Donna S.

AU - Stevenson, Kristen E.

AU - Menghrajani, Kamal

AU - Bolton, Kelly

AU - Fenaux, Pierre

AU - Pellagatti, Andrea

AU - Platzbecker, Uwe

AU - Heuser, Michael

AU - Valent, Peter

AU - Chiba, Shigeru

AU - Miyazaki, Yasushi

AU - Finelli, Carlo

AU - Voso, Maria Teresa

AU - Shih, Lee-Yung

AU - Fontenay, Michaela

AU - Jansen, Joop H.

AU - Cervera, Jose

AU - Atsuta, Yoshiko

AU - Gattermann, Norbert

AU - Ebert, Benjamin L.

AU - Bejar, Rafael

AU - Greenberg, Peter L.

AU - Cazzola, Mario

AU - Lindberg, Eva Hellstrom

AU - Ogawa, Seishi

AU - Papaemmanuil, Elli

PY - 2019

Y1 - 2019

U2 - 10.1182/blood-2019-129392

DO - 10.1182/blood-2019-129392

M3 - Journal Article

SN - 0006-4971

VL - 134

JO - Blood

JF - Blood

ER -