Tropic effect of dexamethasone on goldfish melanocytoma cells: Induction of calcium-dependent but protein synthesis-independent morphological changes

Yung Luen Shih; Shui chou Chou; Chin Wen Chi; T. T. Tchen; Szecheng J. Lo

doi:10.1016/0024-3205(90)90589-J

Tropic effect of dexamethasone on goldfish melanocytoma cells: Induction of calcium-dependent but protein synthesis-independent morphological changes

Yung Luen Shih^*
, Shui chou Chou
, Chin Wen Chi
, T. T. Tchen
, Szecheng J. Lo

^*Corresponding author for this work

National Yang Ming Chiao Tung University
Wayne State University
Veterans General Hospital-Taipei

Research output: Contribution to journal › Journal Article › peer-review

7 Scopus citations

Abstract

Treatment of melanocytoma cells of goldfish origin with dexamethasone leads to rapid morphological changes, flattening of cell body and extension of dendrites. This effect is independent of protein synthesis but requires the presence of extracellular calcium, indicating that it is a "tropic effect" distinct from the typical "trophic effects" of steroid hormones that involve de novo protein synthesis.

Original language	English
Pages (from-to)	313-318
Number of pages	6
Journal	Life Sciences
Volume	47
Issue number	4
DOIs	https://doi.org/10.1016/0024-3205(90)90589-J
State	Published - 1990
Externally published	Yes

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title = "Tropic effect of dexamethasone on goldfish melanocytoma cells: Induction of calcium-dependent but protein synthesis-independent morphological changes",

abstract = "Treatment of melanocytoma cells of goldfish origin with dexamethasone leads to rapid morphological changes, flattening of cell body and extension of dendrites. This effect is independent of protein synthesis but requires the presence of extracellular calcium, indicating that it is a {"}tropic effect{"} distinct from the typical {"}trophic effects{"} of steroid hormones that involve de novo protein synthesis.",

author = "Shih, \{Yung Luen\} and Chou, \{Shui chou\} and Chi, \{Chin Wen\} and Tchen, \{T. T.\} and Lo, \{Szecheng J.\}",

year = "1990",

doi = "10.1016/0024-3205(90)90589-J",

language = "英语",

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pages = "313--318",

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T1 - Tropic effect of dexamethasone on goldfish melanocytoma cells

T2 - Induction of calcium-dependent but protein synthesis-independent morphological changes

AU - Shih, Yung Luen

AU - Chou, Shui chou

AU - Chi, Chin Wen

AU - Tchen, T. T.

AU - Lo, Szecheng J.

PY - 1990

Y1 - 1990

N2 - Treatment of melanocytoma cells of goldfish origin with dexamethasone leads to rapid morphological changes, flattening of cell body and extension of dendrites. This effect is independent of protein synthesis but requires the presence of extracellular calcium, indicating that it is a "tropic effect" distinct from the typical "trophic effects" of steroid hormones that involve de novo protein synthesis.

AB - Treatment of melanocytoma cells of goldfish origin with dexamethasone leads to rapid morphological changes, flattening of cell body and extension of dendrites. This effect is independent of protein synthesis but requires the presence of extracellular calcium, indicating that it is a "tropic effect" distinct from the typical "trophic effects" of steroid hormones that involve de novo protein synthesis.

UR - https://www.scopus.com/pages/publications/0025365277

U2 - 10.1016/0024-3205(90)90589-J

DO - 10.1016/0024-3205(90)90589-J

M3 - 文章

C2 - 2388531

AN - SCOPUS:0025365277

SN - 0024-3205

VL - 47

SP - 313

EP - 318

JO - Life Sciences

JF - Life Sciences

IS - 4

ER -

Tropic effect of dexamethasone on goldfish melanocytoma cells: Induction of calcium-dependent but protein synthesis-independent morphological changes

Abstract

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