TY - JOUR
T1 - Ultrasound-guided core needle biopsy of cervical lymphadenopathy in patients with lymphoma
T2 - The clinical efficacy and factors associated with unsuccessful diagnosis
AU - Huang, Pei Ching
AU - Liu, Chia Yee
AU - Chuang, Wen Yu
AU - Shih, Lee Yung
AU - Wan, Yung Liang
PY - 2010/9
Y1 - 2010/9
N2 - This study attempts to identify factors that influence the success or failure of subclassifying 154 cases of neck lymphoma by ultrasound-guided core needle biopsy (UGCNB). Variables including age, gender, nodal size, cutting needle bore, number of core tissues obtained, presence of nodal necrosis or infarct, fragmentation of the specimens and subclassification of lymphoma were reviewed and statistically analyzed to check if they were related to the success of UGCNB. UGCNB was successful in subclassifying lymphoma in 138 (89.7%) cases, in diagnosing lymphoma in 11 (7.1%) and unsuccessful in diagnosing lymphoma in five (3.2%) cases. No complications were encountered. The factors leading to failure in subclassification included the presence of composite lymphoma (p = 0.001), nodal necrosis or infarct (p = 0.001) and insufficiency or fragmentation of the specimens (p < 0.001). UGCNB is a safe and efficient procedure in subclassifying lymphoma. It may obviate surgical biopsy in 89.7% of cases.
AB - This study attempts to identify factors that influence the success or failure of subclassifying 154 cases of neck lymphoma by ultrasound-guided core needle biopsy (UGCNB). Variables including age, gender, nodal size, cutting needle bore, number of core tissues obtained, presence of nodal necrosis or infarct, fragmentation of the specimens and subclassification of lymphoma were reviewed and statistically analyzed to check if they were related to the success of UGCNB. UGCNB was successful in subclassifying lymphoma in 138 (89.7%) cases, in diagnosing lymphoma in 11 (7.1%) and unsuccessful in diagnosing lymphoma in five (3.2%) cases. No complications were encountered. The factors leading to failure in subclassification included the presence of composite lymphoma (p = 0.001), nodal necrosis or infarct (p = 0.001) and insufficiency or fragmentation of the specimens (p < 0.001). UGCNB is a safe and efficient procedure in subclassifying lymphoma. It may obviate surgical biopsy in 89.7% of cases.
KW - Accuracy and failure of ultrasound-guided core biopsy
KW - Cervical lymphadenopathy
KW - Lymphoma
KW - Subtyping
UR - http://www.scopus.com/inward/record.url?scp=77956039103&partnerID=8YFLogxK
U2 - 10.1016/j.ultrasmedbio.2010.05.018
DO - 10.1016/j.ultrasmedbio.2010.05.018
M3 - 文章
C2 - 20800170
AN - SCOPUS:77956039103
SN - 0301-5629
VL - 36
SP - 1431
EP - 1436
JO - Ultrasound in Medicine and Biology
JF - Ultrasound in Medicine and Biology
IS - 9
ER -