@inproceedings{6c6253bd65714b53a9d60d732165e53a,
title = "UNION: An efficient mapping tool using UniMark with non-overlapping interval indexing strategy",
abstract = "NGS has become a popular research field in biologists because it was able to produce inexpensive and accuracy short biology sequences very fast. NGS technique has been improved to produce long length sequences, more than 100bp, recently with the same quality, accuracy and speed. Thus, tools for short sequences may be not suitable for long length sequences. We propose a new tool called UNION for re-sequencing applications by mapping long length sequences to a reference genome. UNION uses the UniMarker with a non-overlapping interval indexing strategy and a tool, CORAL, to do sequence alignments. For the experiments we randomly cut ten thousands sequences with a length of 512bp from the genome of Trichomonas and also produce mutations/sequence errors for these sequences to simulate different similarities. UNION has been compared with GMAP in terms of speed and accuracy and achieves better performance than that of GMAP.",
keywords = "Genome mapping, NGS, UniMaker, re-seqencing",
author = "Hung, {Che Lun} and Lin, {Chun Yuan} and Hu, {Yu Chen}",
year = "2011",
doi = "10.1007/978-3-642-27157-1_21",
language = "英语",
isbn = "9783642271564",
series = "Communications in Computer and Information Science",
pages = "187--196",
booktitle = "Database Theory and Application, Bio-Science and Bio-Technology -Int. Conf. DTA and BSBT 2011,Held as Part of the Future Generation Inf. Tech. Conf. FGIT 2011, in Conjunction. with GDC 2011,Proc.",
note = "2011 Database Theory and Application,DTA 2011 and Bio-Science and Bio-Technology,BSBT 2011, Held as Part of the Future Generation Information Tech. Conf.FGIT 2011, in Conjunction with GDC 2011 ; Conference date: 08-12-2011 Through 10-12-2011",
}