Unveiling roles of beneficial gut bacteria and optimal diets for health

Suresh Kumar*, Riya Mukherjee, Pratibha Gaur, Élcio Leal, Xiaoming Lyu, Saheem Ahmad, Paridhi Puri, Chung Ming Chang, V. Samuel Raj*, Ramendra Pati Pandey*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

The gut microbiome plays a pivotal role in human health, influencing digestion, immunity, and disease prevention. Beneficial gut bacteria such as Akkermansia muciniphila, Adlercreutzia equolifaciens, and Christensenella minuta contribute to metabolic regulation and immune support through bioactive metabolites like short-chain fatty acids (SCFAs). Dietary patterns rich in prebiotics, fermented foods, and plant-based bioactive compounds, including polyphenols and flavonoids, promote microbiome diversity and stability. However, challenges such as individual variability, bioavailability, dietary adherence, and the dynamic nature of the gut microbiota remain significant. This review synthesizes current insights into gut bacteria’s role in health, emphasizing the mechanisms by which dietary interventions modulate microbiota. Additionally, it highlights advancements in microbiome-targeted therapies and the transformative potential of personalized nutrition, leveraging microbiota profiling and artificial intelligence (AI) to develop tailored dietary strategies for optimizing gut health and mitigating chronic inflammatory disorders. Addressing these challenges requires a multidisciplinary approach that integrates scientific innovation, ethical frameworks, and practical implementation strategies.

Original languageEnglish
Article number1527755
Pages (from-to)1527755
JournalFrontiers in Microbiology
Volume16
DOIs
StatePublished - 2025

Bibliographical note

Copyright © 2025 Kumar, Mukherjee, Gaur, Leal, Lyu, Ahmad, Puri, Chang, Raj and Pandey.

Keywords

  • fatty acid
  • healthy gut bacteria
  • phytochemicals
  • prebiotic foods and probiotic foods
  • probiotics

Fingerprint

Dive into the research topics of 'Unveiling roles of beneficial gut bacteria and optimal diets for health'. Together they form a unique fingerprint.

Cite this