Use of autologous whole blood during internal limiting membrane peeling and macular hole surgery is protective for indocyanine green toxicity

Lan Hsin Chuang, Nan Kai Wang, Ling Yeung, Yen Po Chen, Yih Shiou Hwang, Wei Chi Wu, Chi Chun Lai*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

6 Scopus citations

Abstract

Objective: To compare indocyanine green (ICG)-assisted internal limiting membrane (ILM) peeling with and without autologous whole blood (WB) protection during macular hole repair surgery. Material and methods: We retrospectively reviewed 50 eyes with an idiopathic macular hole. Group 1 contained 22 eyes that underwent ILM peeling with WB protection and group 2 contained 28 eyes that underwent ILM peeling without WB. Anatomic and visual results were compared. Results: After surgery, macular hole closure was achieved in 96% of the group 1 eyes and in 93% of the group 2 eyes. The preoperative mean best-corrected visual acuity (BCVA) was logarithm of the minimum angle of resolution (logMAR) 0.95 in group 1 and logMAR 0.89 in group 2 (p=.544). The postoperative mean BCVA was logMAR 0.57 in group 1 and logMAR 0.92 in group 2 (p=.017). Conclusion: Macular hole surgery protected with WB facilitates improved visual recovery in ICG-assisted ILM peeling.

Original languageEnglish
Pages (from-to)98-104
Number of pages7
JournalCutaneous and Ocular Toxicology
Volume29
Issue number2
DOIs
StatePublished - 06 2010

Keywords

  • Indocyanine green
  • Internal limiting membrane peeling
  • Macular hole repair
  • Whole blood

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