Abstract
Antibiotics resistance is regarded as a potential threat of bacterial infection, making certain bacteria survive and grow during therapy and thus resulting in therapeutic failure. To achieve a rapid screen of antibiotic-resistant bacteria, it is urgent to develop a bacteria culture-independent screening method. Integrating with properties of optically-induced dielectrophoresis (ODEP) in cell manipulation, this paper presented a culture-free screening method for bacteria with different responses to antibiotics treatment by using a light image array with varying light intensities. The results of microbial viability assay and ODEP-based bacteria manipulation have validated the concept proposed in this study.
| Original language | English |
|---|---|
| Title of host publication | 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 1282-1283 |
| Number of pages | 2 |
| ISBN (Electronic) | 9781733419000 |
| State | Published - 2019 |
| Event | 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 - Basel, Switzerland Duration: 27 10 2019 → 31 10 2019 |
Publication series
| Name | 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 |
|---|
Conference
| Conference | 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 |
|---|---|
| Country/Territory | Switzerland |
| City | Basel |
| Period | 27/10/19 → 31/10/19 |
Bibliographical note
Publisher Copyright:© 2019 CBMS-0001.
Keywords
- Antibiotics resistance
- Microbial viability
- Optically-induced dielectrophoresis (ODEP)