Value of Ga-67 SPECT in monitoring the effects of therapy in invasive aspergillosis of the sphenoid sinus

Kai Yuan Tzen; Tzu Chen Yen; Kun Ju Lin

doi:10.1097/00003072-199912000-00006

Value of Ga-67 SPECT in monitoring the effects of therapy in invasive aspergillosis of the sphenoid sinus

Kai Yuan Tzen^*, Tzu Chen Yen, Kun Ju Lin

^*Corresponding author for this work

Research output: Contribution to journal › Journal Article › peer-review

6 Scopus citations

Abstract

Purpose: We report a case of invasive sphenoid sinus aspergillosis clinically presenting as a pituitary mass. Methods: After exploration via the trans-sphenoidal approach and subsequent treatment with amphotericin-B, Ga-67 brain SPECT was performed twice to monitor the therapeutic effect. Results: Three months after antifungal treatment, Ga-67 brain SPECT showed partial resolution of the lesion in the sella turcica region. The patient continued with fluconazole treatment for another 2 months and received another Ga-67 brain SPECT, which showed complete clearing of the previous lesion. Conclusion: Ga-67 brain SPECT may play a potentially useful role in monitoring the therapeutic effect of treatment of invasive sphenoid sinus aspergillosis.

Original language	English
Pages (from-to)	938-941
Number of pages	4
Journal	Clinical Nuclear Medicine
Volume	24
Issue number	12
DOIs	https://doi.org/10.1097/00003072-199912000-00006
State	Published - 12 1999

Keywords

Ga-67 SPECT
Invasive Aspergillosis
Sphenoid Sinus

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10.1097/00003072-199912000-00006

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title = "Value of Ga-67 SPECT in monitoring the effects of therapy in invasive aspergillosis of the sphenoid sinus",

abstract = "Purpose: We report a case of invasive sphenoid sinus aspergillosis clinically presenting as a pituitary mass. Methods: After exploration via the trans-sphenoidal approach and subsequent treatment with amphotericin-B, Ga-67 brain SPECT was performed twice to monitor the therapeutic effect. Results: Three months after antifungal treatment, Ga-67 brain SPECT showed partial resolution of the lesion in the sella turcica region. The patient continued with fluconazole treatment for another 2 months and received another Ga-67 brain SPECT, which showed complete clearing of the previous lesion. Conclusion: Ga-67 brain SPECT may play a potentially useful role in monitoring the therapeutic effect of treatment of invasive sphenoid sinus aspergillosis.",

keywords = "Ga-67 SPECT, Invasive Aspergillosis, Sphenoid Sinus",

author = "Tzen, {Kai Yuan} and Yen, {Tzu Chen} and Lin, {Kun Ju}",

year = "1999",

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volume = "24",

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journal = "Clinical Nuclear Medicine",

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TY - JOUR

T1 - Value of Ga-67 SPECT in monitoring the effects of therapy in invasive aspergillosis of the sphenoid sinus

AU - Tzen, Kai Yuan

AU - Yen, Tzu Chen

AU - Lin, Kun Ju

PY - 1999/12

Y1 - 1999/12

N2 - Purpose: We report a case of invasive sphenoid sinus aspergillosis clinically presenting as a pituitary mass. Methods: After exploration via the trans-sphenoidal approach and subsequent treatment with amphotericin-B, Ga-67 brain SPECT was performed twice to monitor the therapeutic effect. Results: Three months after antifungal treatment, Ga-67 brain SPECT showed partial resolution of the lesion in the sella turcica region. The patient continued with fluconazole treatment for another 2 months and received another Ga-67 brain SPECT, which showed complete clearing of the previous lesion. Conclusion: Ga-67 brain SPECT may play a potentially useful role in monitoring the therapeutic effect of treatment of invasive sphenoid sinus aspergillosis.

AB - Purpose: We report a case of invasive sphenoid sinus aspergillosis clinically presenting as a pituitary mass. Methods: After exploration via the trans-sphenoidal approach and subsequent treatment with amphotericin-B, Ga-67 brain SPECT was performed twice to monitor the therapeutic effect. Results: Three months after antifungal treatment, Ga-67 brain SPECT showed partial resolution of the lesion in the sella turcica region. The patient continued with fluconazole treatment for another 2 months and received another Ga-67 brain SPECT, which showed complete clearing of the previous lesion. Conclusion: Ga-67 brain SPECT may play a potentially useful role in monitoring the therapeutic effect of treatment of invasive sphenoid sinus aspergillosis.

KW - Ga-67 SPECT

KW - Invasive Aspergillosis

KW - Sphenoid Sinus

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SN - 0363-9762

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JO - Clinical Nuclear Medicine

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ER -

Value of Ga-67 SPECT in monitoring the effects of therapy in invasive aspergillosis of the sphenoid sinus

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