Vascular stents in the management of portal venous complications in living donor liver transplantation

Y. F. Cheng, H. Y. Ou, L. L.C. Tsang, C. Y. Yu, T. L. Huang, T. Y. Chen, A. Concejero, C. C. Wang, S. H. Wang, T. S. Lin, Y. W. Liu, C. H. Yang, C. C. Yong, K. W. Chiu, B. Jawan, H. L. Eng, C. L. Chen*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

69 Scopus citations

Abstract

To evaluate the efficacy of stent placement in the treatment of portal vein (PV) stenosis or occlusion in living donor liver transplant (LDLT) recipients, 468 LDLT records were reviewed. Sixteen (10 PV occlusions and 6 stenoses) recipients (age range, 8 months-59 years) were referred for possible interventional angioplasty (dilatation and/or stent) procedures. Stent placement was attempted in all. The approaches used were percutaneous transhepatic (n = 10), percutaneous transsplenic (n = 4), and intraoperative (n = 2). Technical success was achieved in 11 of 16 patients (68.8%). The sizes of the stents used varied from 7 mm to 10 mm in diameter. In the five unsuccessful patients, long-term complete occlusion of the PV with cavernous transformation precluded catherterization. The mean follow-up was 12 months (range, 3-24). The PV stent patency rate was 90.9% (10/11). Rethrombosis and occlusion of the stent and PV occurred in a single recipient who had a cryoperserved vascular graft to reconstruct the PV during the LDLT operation. PV occlusion of >1 year with cavernous transformation seemed to be a factor causing technical failure. In conclusion, early treatment of PV stenosis and occlusion by stenting is an effective treatment in LDLT. Percutaneous transhepatic and transsplenic, and intraoperative techniques are effective approaches depending on the situation.

Original languageEnglish
Pages (from-to)1276-1283
Number of pages8
JournalAmerican Journal of Transplantation
Volume10
Issue number5
DOIs
StatePublished - 05 2010
Externally publishedYes

Keywords

  • Living donor liver transplantation
  • Portal vein complication
  • Portal vein occlusion
  • Stent

Fingerprint

Dive into the research topics of 'Vascular stents in the management of portal venous complications in living donor liver transplantation'. Together they form a unique fingerprint.

Cite this