Abstract
The relationship of Epstein-Barr virus (EBV), type I human T-cell lymphotropic virus (HTLV-I), and parvovirus B19 to histiocytic necrotizing lymphadenitis was studied prospectively in 10 Taiwanese patients using materials obtained by fine-needle aspiration and lymph node biopsy. The presence of EBV was detected by in situ hybridization for EBV-encoded RNA expression. Immunocytochemistry was used to detect virus-encoded protein for EBV and parvovirus B19. DNA in situ hybridization and polymerase chain reaction were performed to determine the existence of HTLV-I provirus. Expressions of EBV-encoded RNA and Fas ligand were detected in all cases. Expression of EBV-encoded protein was identified in only 1 case. Neither HTLV-I nor parvovirus B19 was detected in any case.
| Original language | English |
|---|---|
| Pages (from-to) | 774-781 |
| Number of pages | 8 |
| Journal | American Journal of Clinical Pathology |
| Volume | 113 |
| Issue number | 6 |
| DOIs | |
| State | Published - 2000 |
| Externally published | Yes |
Keywords
- EBV
- Epstein-Barr virus
- Fas ligand
- HTLV-I
- Histiocytic necrotizing lymphadenitis
- Human T-cell lymphotropic virus type I
- Parvovirus B19
