What's new with the old coronaviruses?

Chikara Ogimi, Yae Jean Kim, Emily T. Martin, Hee Jae Huh, Cheng Hsun Chiu, Janet A. Englund*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

46 Scopus citations

Abstract

Coronaviruses contribute to the burden of respiratory diseases in children, frequently manifesting in upper respiratory symptoms considered to be part of the “common cold.” Recent epidemics of novel coronaviruses recognized in the 21st century have highlighted issues of zoonotic origins of transmissible respiratory viruses and potential transmission, disease, and mortality related to these viruses. In this review, we discuss what is known about the virology, epidemiology, and disease associated with pediatric infection with the common community-acquired human coronaviruses, including species 229E, OC43, NL63, and HKU1, and the coronaviruses responsible for past world-wide epidemics due to severe acute respiratory syndrome and Middle East respiratory syndrome coronavirus.

Original languageEnglish
Pages (from-to)210-217
Number of pages8
JournalJournal of the Pediatric Infectious Diseases Society
Volume9
Issue number2
DOIs
StatePublished - 2020
Externally publishedYes

Bibliographical note

Publisher Copyright:
© The Author(s) 2020. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For permissions, please e-mail: [email protected].

Keywords

  • COVID-19
  • Coronavirus
  • MERS
  • Pediatric respiratory viruses
  • SARS

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