A gauge study for dynamic light scattering and differential mobility analyzer instruments

This paper presents the performance of dynamic light scattering (DLS) and differential mobility analyzer (DMA) instruments in measuring nanoparticle size data using a gauge repeatability and reproducibility (GR&R) study based on the mixed model. The adequacy of the measurement process was evaluated using a measure of %GR&R with its confidence interval. The results show that the performance of the DMA instrument is superior to that of the DLS with regard to all variance components of a GR&R study. However, both instruments performed poorly in terms of %GR&R. Therefore, the part and measurement system require further improvement. Using these empirical study applications, this research promotes and maintains measurement quality through procedure analysis.