A High De Ritis Ratio is Associated with Mortality in Adult Trauma Patients

Ching Hua Tsai, Ting Min Hsieh, Shiun Yuan Hsu, Ching Hua Hsieh*

*此作品的通信作者

研究成果: 期刊稿件文章同行評審

摘要

INTRODUCTION: The De Ritis ratio, which is the ratio of aspartate aminotransferase (AST) to alanine aminotransferase (ALT), has been suggested as a potential prognostic marker for various diseases. This study aimed to investigate the association between the De Ritis ratio and in-hospital mortality in adult trauma patients.

METHODS: A total of 17,472 adult trauma patients hospitalized between January 1, 2009, and December 31, 2020, were allocated into groups according to the De Ritis ratio. The normal range of the De Ritis ratio was calculated from 3320 individuals in the National Taiwan Biobank. Statistical analyses were performed using SPSS software.

RESULTS: Patients with a De Ritis ratio >1.6 had a significantly higher in-hospital mortality rate (7.3% vs 1.5%, odds ratio 5.29; Q1-Q3 2.72-10.30; p < 0.001) and a 2.71-fold higher in-hospital mortality rate (Q1-Q3 1.24-5.92; p = 0.012), after adjusting for sex, age, comorbidities, consciousness level, and injury severity, than those with a De Ritis ratio within the reference values.

DISCUSSION: This study revealed that a De Ritis ratio >1.6 may serve as an early prognostic tool to identify adult trauma patients at high risk of in-hospital mortality.

原文英語
頁(從 - 到)879-887
頁數9
期刊Risk Management and Healthcare Policy
16
DOIs
出版狀態已出版 - 2023

文獻附註

© 2023 Tsai et al.

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