@inproceedings{335d7a29f6c74012871d3704f26f85b8,
title = "A microfluidic system enabling continuous characterization of single-cell specific membrane capacitance and cytoplasm conductivity",
abstract = "This paper presents a microfluidic system enabling continuous characterization of specific membrane capacitance (C specific membrane) and cytoplasm conductivity (σ cytoplasm) of single biological cells. In this study, cells were aspirated through a constriction channel while cell elongations and impedance profiles at 1 kHz and 100 kHz were measured simultaneously using microscopy imaging and a lock-in amplifier. Based on the proposed equivalent circuit model, raw data were translated to Cspecific membrane and σcytoplasm, which were 3.67±1.00 vs. 4.53±1.51 μF/cm2 and 0.47±0.09 vs. 0.55±0.14 S/m for the kidney tumor cell line of 786-O (n=302) and the vascular smooth muscle cell line of T2 (n=216), respectively.",
keywords = "Cytoplasm Conductivity, Microfluidics, Single-Cell Analysis, Specific Membrane Capacitance",
author = "Yang Zhao and Deyong Chen and Hao Li and Yana Luo and Bin Deng and Huang, \{Song Bin\} and Chiu, \{Tzu Keng\} and Wu, \{Min Hsien\} and Rong Long and Junbo Wang and Jian Chen",
year = "2013",
doi = "10.1109/NEMS.2013.6559747",
language = "英语",
isbn = "9781467363525",
series = "8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2013",
pages = "344--347",
booktitle = "8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2013",
note = "8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2013 ; Conference date: 07-04-2013 Through 10-04-2013",
}