A new platform for manipulating a single dna molecule by using opticallay-induced dielectrophoresis

Yen Heng Lin, Chen Min Chang, Gwo Bin Lee*

*此作品的通信作者

研究成果: 圖書/報告稿件的類型會議稿件同行評審

1 引文 斯高帕斯(Scopus)

摘要

This paper presents a new platform capable of manipulating a single DNA molecule based on optically-induced dielectrophoretic (ODEP) forces. The ends of λ-phage DNA were bound with polystyrene beads which can be manipulated by optical images generated by a digital projector. The manipulation process of fluorescent-labeled DNA was observed in real time under the ODEP operation. Two kinds of DNA manipulation were conducted including DNA stretching and revolving through the computer-controlled optical images. The stretching force was also measured to estimate the manipulation ability of DNA molecule in this platform. The maximum stretching force was estimated to be about 49.73 pN when binding with 10 μm polystyrene beads. The developed platform may be a promising tool for single DNA molecule investigation.

原文英語
主出版物標題TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems
頁面1590-1593
頁數4
DOIs
出版狀態已出版 - 2009
對外發佈
事件TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems - Denver, CO, 美國
持續時間: 21 06 200925 06 2009

出版系列

名字TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems

Conference

ConferenceTRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems
國家/地區美國
城市Denver, CO
期間21/06/0925/06/09

指紋

深入研究「A new platform for manipulating a single dna molecule by using opticallay-induced dielectrophoresis」主題。共同形成了獨特的指紋。

引用此