Advances in miniaturized instruments for genomics

Cihun Siyong Alex Gong, Kin Fong Lei*

*此作品的通信作者

研究成果: 期刊稿件文獻綜述同行評審

9 引文 斯高帕斯(Scopus)

摘要

In recent years, a lot of demonstrations of the miniaturized instruments were reported for genomic applications. They provided the advantages of miniaturization, automation, sensitivity, and specificity for the development of point-of-care diagnostics. The aim of this paper is to report on recent developments on miniaturized instruments for genomic applications. Based on the mature development of microfabrication, microfluidic systems have been demonstrated for various genomic detections. Since one of the objectives of miniaturized instruments is for the development of point-of-care device, impedimetric detection is found to be a promising technique for this purpose. An in-depth discussion of the impedimetric circuits and systems will be included to provide total consideration of the miniaturized instruments and their potential application towards real-time portable imaging in the "-omics" era. The current excellent demonstrations suggest a solid foundation for the development of practical and widespread point-of-care genomic diagnostic devices.

原文英語
文章編號734675
期刊BioMed Research International
2014
DOIs
出版狀態已出版 - 2014

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