An integrated microfluidic system for rapid detection and typing of live bacteria from human joint fluidic samples

Wen Hsin Chang; Chih Hung Wang; Chih Lin Lin; Jiunn Jong Wu; Mel S. Lee; Gwo Bin Lee

doi:10.1109/NANO.2014.6968166

An integrated microfluidic system for rapid detection and typing of live bacteria from human joint fluidic samples

Wen Hsin Chang, Chih Hung Wang, Chih Lin Lin, Jiunn Jong Wu, Mel S. Lee^*, Gwo Bin Lee

^*此作品的通信作者

研究成果: 圖書/報告稿件的類型 › 會議稿件 › 同行評審

摘要

Periprosthetic joint infection (PJI) is a devastating complication after arthroplasty. Two-stage reimplantation procedure is the most common practice to prevent the reoccurrence of PJI. However, it should be assisted by a rapid, accurate and comprehensive bacteria detection tool. In this study, a new integrated microfluidic system capable of performing sample pre-treatment, a nanogold detection to provide live bacteria information (30 minutes) and a PCR reaction (further 40 minutes) to distinguished bacteria types for antibiotic treatment automatically without human intervention is proposed. The experimental results demonstrated that this powerful tool can serve as a base for clinical decision-making in the near future.

原文	英語
主出版物標題	Proceedings of the IEEE Conference on Nanotechnology
發行者	Institute of Electrical and Electronics Engineers Inc.
頁面	752-755
頁數	4
ISBN（電子）	9781479956227
DOIs	https://doi.org/10.1109/NANO.2014.6968166
出版狀態	已出版 - 26 11 2014
對外發佈	是
事件	2014 14th IEEE International Conference on Nanotechnology, IEEE-NANO 2014 - Toronto, 加拿大持續時間: 18 08 2014 → 21 08 2014

出版系列

名字	Proceedings of the IEEE Conference on Nanotechnology
ISSN（電子）	1944-9399

Conference

Conference	2014 14th IEEE International Conference on Nanotechnology, IEEE-NANO 2014
國家/地區	加拿大
城市	Toronto
期間	18/08/14 → 21/08/14

文獻附註

Publisher Copyright:
© 2014 IEEE.

存取文件

10.1109/NANO.2014.6968166

其它文件與鏈接

Link to publication in Scopus

引用此

Chang, W. H., Wang, C. H., Lin, C. L., Wu, J. J., Lee, M. S., & Lee, G. B. (2014). An integrated microfluidic system for rapid detection and typing of live bacteria from human joint fluidic samples. 於 Proceedings of the IEEE Conference on Nanotechnology (頁 752-755). 文章 6968166 (Proceedings of the IEEE Conference on Nanotechnology). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/NANO.2014.6968166

@inproceedings{786bd82f1957480aa5b5e9faa0906960,

title = "An integrated microfluidic system for rapid detection and typing of live bacteria from human joint fluidic samples",

abstract = "Periprosthetic joint infection (PJI) is a devastating complication after arthroplasty. Two-stage reimplantation procedure is the most common practice to prevent the reoccurrence of PJI. However, it should be assisted by a rapid, accurate and comprehensive bacteria detection tool. In this study, a new integrated microfluidic system capable of performing sample pre-treatment, a nanogold detection to provide live bacteria information (30 minutes) and a PCR reaction (further 40 minutes) to distinguished bacteria types for antibiotic treatment automatically without human intervention is proposed. The experimental results demonstrated that this powerful tool can serve as a base for clinical decision-making in the near future.",

author = "Chang, {Wen Hsin} and Wang, {Chih Hung} and Lin, {Chih Lin} and Wu, {Jiunn Jong} and Lee, {Mel S.} and Lee, {Gwo Bin}",

note = "Publisher Copyright: {\textcopyright} 2014 IEEE.; 2014 14th IEEE International Conference on Nanotechnology, IEEE-NANO 2014 ; Conference date: 18-08-2014 Through 21-08-2014",

year = "2014",

month = nov,

day = "26",

doi = "10.1109/NANO.2014.6968166",

language = "英语",

series = "Proceedings of the IEEE Conference on Nanotechnology",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

pages = "752--755",

booktitle = "Proceedings of the IEEE Conference on Nanotechnology",

address = "美国",

}

Chang, WH, Wang, CH, Lin, CL, Wu, JJ, Lee, MS & Lee, GB 2014, An integrated microfluidic system for rapid detection and typing of live bacteria from human joint fluidic samples. 於 Proceedings of the IEEE Conference on Nanotechnology., 6968166, Proceedings of the IEEE Conference on Nanotechnology, Institute of Electrical and Electronics Engineers Inc., 頁 752-755, 2014 14th IEEE International Conference on Nanotechnology, IEEE-NANO 2014, Toronto, 加拿大, 18/08/14. https://doi.org/10.1109/NANO.2014.6968166

An integrated microfluidic system for rapid detection and typing of live bacteria from human joint fluidic samples. / Chang, Wen Hsin; Wang, Chih Hung; Lin, Chih Lin 等.
Proceedings of the IEEE Conference on Nanotechnology. Institute of Electrical and Electronics Engineers Inc., 2014. p. 752-755 6968166 (Proceedings of the IEEE Conference on Nanotechnology).

研究成果: 圖書/報告稿件的類型 › 會議稿件 › 同行評審

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T1 - An integrated microfluidic system for rapid detection and typing of live bacteria from human joint fluidic samples

AU - Chang, Wen Hsin

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AU - Lin, Chih Lin

AU - Wu, Jiunn Jong

AU - Lee, Mel S.

AU - Lee, Gwo Bin

PY - 2014/11/26

Y1 - 2014/11/26

N2 - Periprosthetic joint infection (PJI) is a devastating complication after arthroplasty. Two-stage reimplantation procedure is the most common practice to prevent the reoccurrence of PJI. However, it should be assisted by a rapid, accurate and comprehensive bacteria detection tool. In this study, a new integrated microfluidic system capable of performing sample pre-treatment, a nanogold detection to provide live bacteria information (30 minutes) and a PCR reaction (further 40 minutes) to distinguished bacteria types for antibiotic treatment automatically without human intervention is proposed. The experimental results demonstrated that this powerful tool can serve as a base for clinical decision-making in the near future.

AB - Periprosthetic joint infection (PJI) is a devastating complication after arthroplasty. Two-stage reimplantation procedure is the most common practice to prevent the reoccurrence of PJI. However, it should be assisted by a rapid, accurate and comprehensive bacteria detection tool. In this study, a new integrated microfluidic system capable of performing sample pre-treatment, a nanogold detection to provide live bacteria information (30 minutes) and a PCR reaction (further 40 minutes) to distinguished bacteria types for antibiotic treatment automatically without human intervention is proposed. The experimental results demonstrated that this powerful tool can serve as a base for clinical decision-making in the near future.

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U2 - 10.1109/NANO.2014.6968166

DO - 10.1109/NANO.2014.6968166

M3 - 会议稿件

AN - SCOPUS:84919476064

T3 - Proceedings of the IEEE Conference on Nanotechnology

SP - 752

EP - 755

BT - Proceedings of the IEEE Conference on Nanotechnology

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 2014 14th IEEE International Conference on Nanotechnology, IEEE-NANO 2014

Y2 - 18 August 2014 through 21 August 2014

ER -

Chang WH, Wang CH, Lin CL, Wu JJ, Lee MS, Lee GB. An integrated microfluidic system for rapid detection and typing of live bacteria from human joint fluidic samples. 於 Proceedings of the IEEE Conference on Nanotechnology. Institute of Electrical and Electronics Engineers Inc. 2014. p. 752-755. 6968166. (Proceedings of the IEEE Conference on Nanotechnology). doi: 10.1109/NANO.2014.6968166

An integrated microfluidic system for rapid detection and typing of live bacteria from human joint fluidic samples

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