An integrated microfluidic system for rapid detection and typing of live bacteria from human joint fluidic samples

Wen Hsin Chang; Chih Hung Wang; Chih Lin Lin; Jiunn Jong Wu; Mel S. Lee; Gwo Bin Lee

doi:10.1109/NANO.2014.6968166

An integrated microfluidic system for rapid detection and typing of live bacteria from human joint fluidic samples

Wen Hsin Chang
, Chih Hung Wang
, Chih Lin Lin
, Jiunn Jong Wu
, Mel S. Lee^*
, Gwo Bin Lee

^*此作品的通信作者

National Tsing Hua University
National Cheng Kung University
Chang Gung Memorial Hospital

研究成果: 圖書/報告稿件的類型 › 會議稿件 › 同行評審

摘要

Periprosthetic joint infection (PJI) is a devastating complication after arthroplasty. Two-stage reimplantation procedure is the most common practice to prevent the reoccurrence of PJI. However, it should be assisted by a rapid, accurate and comprehensive bacteria detection tool. In this study, a new integrated microfluidic system capable of performing sample pre-treatment, a nanogold detection to provide live bacteria information (30 minutes) and a PCR reaction (further 40 minutes) to distinguished bacteria types for antibiotic treatment automatically without human intervention is proposed. The experimental results demonstrated that this powerful tool can serve as a base for clinical decision-making in the near future.

原文	英語
主出版物標題	Proceedings of the IEEE Conference on Nanotechnology
發行者	Institute of Electrical and Electronics Engineers Inc.
頁面	752-755
頁數	4
ISBN（電子）	9781479956227
DOIs	https://doi.org/10.1109/NANO.2014.6968166
出版狀態	已出版 - 26 11 2014
對外發佈	是
事件	2014 14th IEEE International Conference on Nanotechnology, IEEE-NANO 2014 - Toronto, 加拿大持續時間: 18 08 2014 → 21 08 2014

出版系列

名字	Proceedings of the IEEE Conference on Nanotechnology
ISSN（電子）	1944-9399

Conference

Conference	2014 14th IEEE International Conference on Nanotechnology, IEEE-NANO 2014
國家/地區	加拿大
城市	Toronto
期間	18/08/14 → 21/08/14

文獻附註

Publisher Copyright:
© 2014 IEEE.

存取文件

10.1109/NANO.2014.6968166

其它文件與鏈接

Link to publication in Scopus

引用此

Chang, W. H., Wang, C. H., Lin, C. L., Wu, J. J., Lee, M. S., & Lee, G. B. (2014). An integrated microfluidic system for rapid detection and typing of live bacteria from human joint fluidic samples. 於 Proceedings of the IEEE Conference on Nanotechnology (頁 752-755). 文章 6968166 (Proceedings of the IEEE Conference on Nanotechnology). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/NANO.2014.6968166

@inproceedings{786bd82f1957480aa5b5e9faa0906960,

title = "An integrated microfluidic system for rapid detection and typing of live bacteria from human joint fluidic samples",

abstract = "Periprosthetic joint infection (PJI) is a devastating complication after arthroplasty. Two-stage reimplantation procedure is the most common practice to prevent the reoccurrence of PJI. However, it should be assisted by a rapid, accurate and comprehensive bacteria detection tool. In this study, a new integrated microfluidic system capable of performing sample pre-treatment, a nanogold detection to provide live bacteria information (30 minutes) and a PCR reaction (further 40 minutes) to distinguished bacteria types for antibiotic treatment automatically without human intervention is proposed. The experimental results demonstrated that this powerful tool can serve as a base for clinical decision-making in the near future.",

author = "Chang, \{Wen Hsin\} and Wang, \{Chih Hung\} and Lin, \{Chih Lin\} and Wu, \{Jiunn Jong\} and Lee, \{Mel S.\} and Lee, \{Gwo Bin\}",

note = "Publisher Copyright: {\textcopyright} 2014 IEEE.; 2014 14th IEEE International Conference on Nanotechnology, IEEE-NANO 2014 ; Conference date: 18-08-2014 Through 21-08-2014",

year = "2014",

month = nov,

day = "26",

doi = "10.1109/NANO.2014.6968166",

language = "英语",

series = "Proceedings of the IEEE Conference on Nanotechnology",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

pages = "752--755",

booktitle = "Proceedings of the IEEE Conference on Nanotechnology",

address = "美国",

}

Chang, WH, Wang, CH, Lin, CL, Wu, JJ, Lee, MS & Lee, GB 2014, An integrated microfluidic system for rapid detection and typing of live bacteria from human joint fluidic samples. 於 Proceedings of the IEEE Conference on Nanotechnology., 6968166, Proceedings of the IEEE Conference on Nanotechnology, Institute of Electrical and Electronics Engineers Inc., 頁 752-755, 2014 14th IEEE International Conference on Nanotechnology, IEEE-NANO 2014, Toronto, 加拿大, 18/08/14. https://doi.org/10.1109/NANO.2014.6968166

An integrated microfluidic system for rapid detection and typing of live bacteria from human joint fluidic samples. / Chang, Wen Hsin; Wang, Chih Hung; Lin, Chih Lin 等.
Proceedings of the IEEE Conference on Nanotechnology. Institute of Electrical and Electronics Engineers Inc., 2014. p. 752-755 6968166 (Proceedings of the IEEE Conference on Nanotechnology).

研究成果: 圖書/報告稿件的類型 › 會議稿件 › 同行評審

TY - GEN

T1 - An integrated microfluidic system for rapid detection and typing of live bacteria from human joint fluidic samples

AU - Chang, Wen Hsin

AU - Wang, Chih Hung

AU - Lin, Chih Lin

AU - Wu, Jiunn Jong

AU - Lee, Mel S.

AU - Lee, Gwo Bin

PY - 2014/11/26

Y1 - 2014/11/26

N2 - Periprosthetic joint infection (PJI) is a devastating complication after arthroplasty. Two-stage reimplantation procedure is the most common practice to prevent the reoccurrence of PJI. However, it should be assisted by a rapid, accurate and comprehensive bacteria detection tool. In this study, a new integrated microfluidic system capable of performing sample pre-treatment, a nanogold detection to provide live bacteria information (30 minutes) and a PCR reaction (further 40 minutes) to distinguished bacteria types for antibiotic treatment automatically without human intervention is proposed. The experimental results demonstrated that this powerful tool can serve as a base for clinical decision-making in the near future.

AB - Periprosthetic joint infection (PJI) is a devastating complication after arthroplasty. Two-stage reimplantation procedure is the most common practice to prevent the reoccurrence of PJI. However, it should be assisted by a rapid, accurate and comprehensive bacteria detection tool. In this study, a new integrated microfluidic system capable of performing sample pre-treatment, a nanogold detection to provide live bacteria information (30 minutes) and a PCR reaction (further 40 minutes) to distinguished bacteria types for antibiotic treatment automatically without human intervention is proposed. The experimental results demonstrated that this powerful tool can serve as a base for clinical decision-making in the near future.

UR - https://www.scopus.com/pages/publications/84919476064

U2 - 10.1109/NANO.2014.6968166

DO - 10.1109/NANO.2014.6968166

M3 - 会议稿件

AN - SCOPUS:84919476064

T3 - Proceedings of the IEEE Conference on Nanotechnology

SP - 752

EP - 755

BT - Proceedings of the IEEE Conference on Nanotechnology

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 2014 14th IEEE International Conference on Nanotechnology, IEEE-NANO 2014

Y2 - 18 August 2014 through 21 August 2014

ER -

Chang WH, Wang CH, Lin CL, Wu JJ, Lee MS, Lee GB. An integrated microfluidic system for rapid detection and typing of live bacteria from human joint fluidic samples. 於 Proceedings of the IEEE Conference on Nanotechnology. Institute of Electrical and Electronics Engineers Inc. 2014. p. 752-755. 6968166. (Proceedings of the IEEE Conference on Nanotechnology). doi: 10.1109/NANO.2014.6968166

An integrated microfluidic system for rapid detection and typing of live bacteria from human joint fluidic samples

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