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Automatic extraction of information about the molecular interactions in biological pathways from texts based on ontology and semantic processing

  • Yu Ting Huang*
  • , Hsiang Yuan Yeh
  • , Shih Wu Cheng
  • , Chien Chih Tu
  • , Chi Li Kuo
  • , Von Wun Soo
  • *此作品的通信作者
  • National Tsing Hua University
  • National University of Kaohsiung

研究成果: 圖書/報告稿件的類型會議稿件同行評審

5 引文 斯高帕斯(Scopus)

摘要

We develop a framework using ontology inference and semantic processing techniques to help biologists to extract knowledge directly from a large scale of biological literature in NCBI PubMed. The system integrated various sharable thesauri of WordNet, MeSH (Medical Subject Heading), and GO (Gene ontology) to support the automatic semantic annotation and analysis. The natural language processing and semantic processing are facilitated by the ontological inference, and the system could automatically extract the correct molecular interactions from the complex sentences in an abstract automatically. It facilitates the biologists not only to save time and efforts to construct and analyze biological pathways, but also to discover the novel molecular interactions by comparing the information extracted from the literature with that in such existing path way database as KEGG. We evaluated the system performance based on the pathways in Apoptosis domain.

原文英語
主出版物標題2006 IEEE International Conference on Systems, Man and Cybernetics
發行者Institute of Electrical and Electronics Engineers Inc.
頁面3679-3684
頁數6
ISBN(列印)1424401003, 9781424401000
DOIs
出版狀態已出版 - 2006
對外發佈
事件2006 IEEE International Conference on Systems, Man and Cybernetics - Taipei, 台灣
持續時間: 08 10 200611 10 2006

出版系列

名字Conference Proceedings - IEEE International Conference on Systems, Man and Cybernetics
5
ISSN(列印)1062-922X

Conference

Conference2006 IEEE International Conference on Systems, Man and Cybernetics
國家/地區台灣
城市Taipei
期間08/10/0611/10/06

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