TY - JOUR
T1 - Cadmium and cardiovascular disease
T2 - An overview of pathophysiology, epidemiology, therapy, and predictive value
AU - Lin, Hung Chen
AU - Hao, Wei Ming
AU - Chu, Pao Hsien
N1 - Publisher Copyright:
© 2021 Sociedade Portuguesa de Cardiologia
PY - 2021/8
Y1 - 2021/8
N2 - Cadmium is a widely distributed toxic heavy metal that has been associated with many diseases including chronic renal dysfunction, osteomalacia, acute heart failure, secondary hypertension, and atherosclerosis. Although several studies have suggested that cadmium may affect multiple systems by inducing lipid per oxidation in cells and disturbing the antioxidant system, the mechanism by which cadmium affects the cardiovascular system remains unclear. Recent studies on heart failure and acute myocardial infarction have shown that cadmium has good predictive ability for mortality in patients with cardiovascular disease. In this study, we briefly review the role of cadmium in cardiovascular disease, which may prompt further studies to investigate the potential association between cadmium and mortality in patients with cardiovascular disease.
AB - Cadmium is a widely distributed toxic heavy metal that has been associated with many diseases including chronic renal dysfunction, osteomalacia, acute heart failure, secondary hypertension, and atherosclerosis. Although several studies have suggested that cadmium may affect multiple systems by inducing lipid per oxidation in cells and disturbing the antioxidant system, the mechanism by which cadmium affects the cardiovascular system remains unclear. Recent studies on heart failure and acute myocardial infarction have shown that cadmium has good predictive ability for mortality in patients with cardiovascular disease. In this study, we briefly review the role of cadmium in cardiovascular disease, which may prompt further studies to investigate the potential association between cadmium and mortality in patients with cardiovascular disease.
KW - Acute myocardial infarction
KW - Cadmium
KW - Cardiovascular disease
KW - Heart failure
UR - http://www.scopus.com/inward/record.url?scp=85107443248&partnerID=8YFLogxK
U2 - 10.1016/j.repc.2021.01.009
DO - 10.1016/j.repc.2021.01.009
M3 - 文献综述
C2 - 34392906
AN - SCOPUS:85107443248
SN - 0870-2551
VL - 40
SP - 611
EP - 617
JO - Revista Portuguesa de Cardiologia
JF - Revista Portuguesa de Cardiologia
IS - 8
ER -
