TY - JOUR
T1 - Comparing different non-invasive brain stimulation interventions for bipolar depression treatment
T2 - A network meta-analysis of randomized controlled trials
AU - Hsu, Chih Wei
AU - Chou, Po Han
AU - Brunoni, Andre R.
AU - Hung, Kuo Chuan
AU - Tseng, Ping Tao
AU - Liang, Chih Sung
AU - Carvalho, Andre F.
AU - Vieta, Eduard
AU - Tu, Yu Kang
AU - Lin, Pao Yen
AU - Chu, Che Sheng
AU - Hsu, Tien Wei
AU - Chen, Yang Chieh Brian
AU - Li, Cheng Ta
N1 - Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.
PY - 2024/1
Y1 - 2024/1
N2 - Non-invasive brain stimulation (NIBS) is a promising treatment for bipolar depression. We systematically searched for randomized controlled trials on NIBS for treating bipolar depression (INPLASY No: 202340019). Eighteen articles (N = 617) were eligible for network meta-analysis. Effect sizes were reported as standardized mean differences (SMDs) or odds ratios (ORs) with 95% confidence intervals (CIs). Anodal transcranial direct current stimulation over F3 plus cathodal transcranial direct current stimulation over F4 (a-tDCS-F3 +c-tDCS-F4; SMD = −1.18, 95%CIs = −1.66 to −0.69, N = 77), high-definition tDCS over F3 (HD-tDCS-F3; −1.17, −2.00 to −0.35, 25), high frequency deep transcranial magnetic stimulation (HF-dTMS; −0.81, −1.62 to −0.001, 25), and high frequency repetitive TMS over F3 plus low frequency repetitive TMS over F4 (HF-rTMS-F3 +LF-rTMS-F4; −0.77, −1.43 to −0.11, 38) significantly improved depressive symptoms compared to sham controls. Only a-tDCS-F3 +c-tDCS-F4 (OR = 4.53, 95%CIs = 1.51–13.65) and HF-rTMS-F3 +LF-rTMS-F4 (4.69, 1.02–21.56) showed higher response rates. No active NIBS interventions exhibited significant differences in dropout or side effect rates, compared with sham controls.
AB - Non-invasive brain stimulation (NIBS) is a promising treatment for bipolar depression. We systematically searched for randomized controlled trials on NIBS for treating bipolar depression (INPLASY No: 202340019). Eighteen articles (N = 617) were eligible for network meta-analysis. Effect sizes were reported as standardized mean differences (SMDs) or odds ratios (ORs) with 95% confidence intervals (CIs). Anodal transcranial direct current stimulation over F3 plus cathodal transcranial direct current stimulation over F4 (a-tDCS-F3 +c-tDCS-F4; SMD = −1.18, 95%CIs = −1.66 to −0.69, N = 77), high-definition tDCS over F3 (HD-tDCS-F3; −1.17, −2.00 to −0.35, 25), high frequency deep transcranial magnetic stimulation (HF-dTMS; −0.81, −1.62 to −0.001, 25), and high frequency repetitive TMS over F3 plus low frequency repetitive TMS over F4 (HF-rTMS-F3 +LF-rTMS-F4; −0.77, −1.43 to −0.11, 38) significantly improved depressive symptoms compared to sham controls. Only a-tDCS-F3 +c-tDCS-F4 (OR = 4.53, 95%CIs = 1.51–13.65) and HF-rTMS-F3 +LF-rTMS-F4 (4.69, 1.02–21.56) showed higher response rates. No active NIBS interventions exhibited significant differences in dropout or side effect rates, compared with sham controls.
KW - Antidepressant
KW - Bipolar disorder
KW - Theta burst stimulation
KW - Transcranial electrical stimulation
KW - Transcranial Magnetic Stimulation
KW - Transcranial Direct Current Stimulation
KW - Humans
KW - Bipolar Disorder/therapy
KW - Brain/physiology
KW - Network Meta-Analysis
KW - Randomized Controlled Trials as Topic
UR - https://www.scopus.com/pages/publications/85179089162
U2 - 10.1016/j.neubiorev.2023.105483
DO - 10.1016/j.neubiorev.2023.105483
M3 - 文献综述
C2 - 38056187
AN - SCOPUS:85179089162
SN - 0149-7634
VL - 156
SP - 105483
JO - Neuroscience and Biobehavioral Reviews
JF - Neuroscience and Biobehavioral Reviews
M1 - 105483
ER -