Cutaneous intravascular NK-cell lymphoma: Report of a rare variant associated with Epstein-Barr virus

Tseng Tong Kuo*, Ming Jing Chen, Ming Chung Kuo

*此作品的通信作者

研究成果: 期刊稿件文章同行評審

48 引文 斯高帕斯(Scopus)

摘要

Intravascular lymphoma (IVL) is a rare variant of non-Hodgkin lymphoma with a predilection for skin and brain. Except a few cases of T-cell lineage, most of the reported cases were large B-cell lymphomas. We encountered a case of cutaneous IVL in a 71-year-old woman presenting with multiple erythematous patches and nodules on her trunk and extremities. The intravascular large cells showed an immunophenotype of CD3ε+, CD5-, CD20 -, CD30-, CD56+, and TIA-1+. The lymphoma cells were also positive for Epstein-Barr virus by Epstein-Barr virus-encoded RNA in situ hybridization test and the T-cell receptor gene was germline. This IVL differs from nasal type NK/T-cell lymphoma only by its intravascular nature. Only 3 cases of intravascular NK-cell lymphoma have been reported before. Because this variant is extremely rare, our case is documented and compared with the 3 previously reported cases.

原文英語
頁(從 - 到)1197-1201
頁數5
期刊American Journal of Surgical Pathology
30
發行號9
DOIs
出版狀態已出版 - 09 2006

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