Cyclopeptides with anti-inflammatory activity from seeds of Annona montana

Pei Hsuan Chuang; Pei Wen Hsieh; Yu Liang Yang; Kuo Feng Hua; Fang Rong Chang; Jentaie Shiea; Shih Hsiung Wu; Yang Chang Wu

doi:10.1021/np8001282

Cyclopeptides with anti-inflammatory activity from seeds of Annona montana

Pei Hsuan Chuang, Pei Wen Hsieh, Yu Liang Yang, Kuo Feng Hua, Fang Rong Chang, Jentaie Shiea, Shih Hsiung Wu, Yang Chang Wu^*

^*此作品的通信作者

中醫學系(含學士班、天然藥物、傳統中醫藥碩士班)

研究成果: 期刊稿件 › 文章 › 同行評審

52 引文斯高帕斯（Scopus）

摘要

Four new cyclopeptides, cyclomontanins A-D (1-4), annomuricatin C (5), and (+)-corytuberine were isolated from a methanol extract of Annona montana seeds. Their structures were elucidated by 2D NMR analysis, ESIMS/MS fragment evidence, and chemical means. The structure of 1 was confirmed by synthesis. Compounds 1, 3, and 4 exhibited anti-inflammatory activity in vitro using the J774.1 macrophage model.

原文	英語
頁（從 - 到）	1365-1370
頁數	6
期刊	Journal of Natural Products
卷	71
發行號	8
DOIs	https://doi.org/10.1021/np8001282
出版狀態	已出版 - 08 2008

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10.1021/np8001282

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title = "Cyclopeptides with anti-inflammatory activity from seeds of Annona montana",

abstract = "Four new cyclopeptides, cyclomontanins A-D (1-4), annomuricatin C (5), and (+)-corytuberine were isolated from a methanol extract of Annona montana seeds. Their structures were elucidated by 2D NMR analysis, ESIMS/MS fragment evidence, and chemical means. The structure of 1 was confirmed by synthesis. Compounds 1, 3, and 4 exhibited anti-inflammatory activity in vitro using the J774.1 macrophage model.",

author = "Chuang, {Pei Hsuan} and Hsieh, {Pei Wen} and Yang, {Yu Liang} and Hua, {Kuo Feng} and Chang, {Fang Rong} and Jentaie Shiea and Wu, {Shih Hsiung} and Wu, {Yang Chang}",

year = "2008",

month = aug,

doi = "10.1021/np8001282",

language = "英语",

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TY - JOUR

T1 - Cyclopeptides with anti-inflammatory activity from seeds of Annona montana

AU - Chuang, Pei Hsuan

AU - Hsieh, Pei Wen

AU - Yang, Yu Liang

AU - Hua, Kuo Feng

AU - Chang, Fang Rong

AU - Shiea, Jentaie

AU - Wu, Shih Hsiung

AU - Wu, Yang Chang

PY - 2008/8

Y1 - 2008/8

N2 - Four new cyclopeptides, cyclomontanins A-D (1-4), annomuricatin C (5), and (+)-corytuberine were isolated from a methanol extract of Annona montana seeds. Their structures were elucidated by 2D NMR analysis, ESIMS/MS fragment evidence, and chemical means. The structure of 1 was confirmed by synthesis. Compounds 1, 3, and 4 exhibited anti-inflammatory activity in vitro using the J774.1 macrophage model.

AB - Four new cyclopeptides, cyclomontanins A-D (1-4), annomuricatin C (5), and (+)-corytuberine were isolated from a methanol extract of Annona montana seeds. Their structures were elucidated by 2D NMR analysis, ESIMS/MS fragment evidence, and chemical means. The structure of 1 was confirmed by synthesis. Compounds 1, 3, and 4 exhibited anti-inflammatory activity in vitro using the J774.1 macrophage model.

UR - http://www.scopus.com/inward/record.url?scp=51849113677&partnerID=8YFLogxK

U2 - 10.1021/np8001282

DO - 10.1021/np8001282

M3 - 文章

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AN - SCOPUS:51849113677

SN - 0163-3864

VL - 71

SP - 1365

EP - 1370

JO - Journal of Natural Products

JF - Journal of Natural Products

IS - 8

ER -

Cyclopeptides with anti-inflammatory activity from seeds of Annona montana

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