Cyclosporine enhances vasorelaxation in coronary but not pulmonary artery after 16-hour preservation with UW solution

Y. Chu, Y. C. Wu, Y. C. Chou, H. P. Liu, J. J. Chu, P. J. Lin*

*此作品的通信作者

研究成果: 期刊稿件文章同行評審

2 引文 斯高帕斯(Scopus)

摘要

Cyclosporine (CsA), a calcineurin inhibitor, has been associated with endothelial dysfunction in transplant patients. Human and in vitro studies suggest that CsA produces endothelial dysfunction by impairing vascular endothelium-dependent relaxation. However, little is know about the CsA effects to modulate the vasorelaxation after prolonged graft preservation. In this study using a protocol designed to eliminate the influences of infusion pressure and shear stress, we evaluated the effect of CsA on vasorelaxation of coronary and pulmonary arteries after 16-hour University of Wisconsin (UW) solution preservation.

原文英語
頁(從 - 到)3139-3141
頁數3
期刊Transplantation Proceedings
35
發行號8
DOIs
出版狀態已出版 - 12 2003
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