摘要
Cyclosporine (CsA), a calcineurin inhibitor, has been associated with endothelial dysfunction in transplant patients. Human and in vitro studies suggest that CsA produces endothelial dysfunction by impairing vascular endothelium-dependent relaxation. However, little is know about the CsA effects to modulate the vasorelaxation after prolonged graft preservation. In this study using a protocol designed to eliminate the influences of infusion pressure and shear stress, we evaluated the effect of CsA on vasorelaxation of coronary and pulmonary arteries after 16-hour University of Wisconsin (UW) solution preservation.
原文 | 英語 |
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頁(從 - 到) | 3139-3141 |
頁數 | 3 |
期刊 | Transplantation Proceedings |
卷 | 35 |
發行號 | 8 |
DOIs | |
出版狀態 | 已出版 - 12 2003 |
對外發佈 | 是 |