Cytotoxic principles from the leaves of Tithonia diversifolia

Tian Shung Wu; Li Shian Shi; Ping Chung Kuo; Yann Lii Leu; Meei Jen Liou; Pei Lin Wu; Yang Chang Wu; Song Chou Iou; Yuh Pan Chen; Hsien Chang Chang

Cytotoxic principles from the leaves of Tithonia diversifolia

Tian Shung Wu^*
, Li Shian Shi
, Ping Chung Kuo
, Yann Lii Leu
, Meei Jen Liou
, Pei Lin Wu
, Yang Chang Wu
, Song Chou Iou
, Yuh Pan Chen
, Hsien Chang Chang

^*此作品的通信作者

National Cheng Kung University

研究成果: 期刊稿件 › 文章 › 同行評審

12 引文斯高帕斯（Scopus）

摘要

Three compounds, acetyltagitinin E (1), tagitinin-F (2) and hispidulin (3), were isolated from the leaves of Tithonia diversifolia. The stereochemistry of 1 was further supported by X-ray crystallography. The cytotoxicity of these compounds was also determined. Compounds 1 and 2 showed selective cytotoxicity to Hep G2 human hepatocellular carcinoma cells.

原文	英語
頁（從 - 到）	217-223
頁數	7
期刊	Chinese Pharmaceutical Journal
卷	53
發行號	5
出版狀態	已出版 - 2001
對外發佈	是

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@article{72963ccb6cd848569a755c767152c7f4,

title = "Cytotoxic principles from the leaves of Tithonia diversifolia",

abstract = "Three compounds, acetyltagitinin E (1), tagitinin-F (2) and hispidulin (3), were isolated from the leaves of Tithonia diversifolia. The stereochemistry of 1 was further supported by X-ray crystallography. The cytotoxicity of these compounds was also determined. Compounds 1 and 2 showed selective cytotoxicity to Hep G2 human hepatocellular carcinoma cells.",

keywords = "Acetyltagitinin E, Compositae, Sesquiterpene lactone, Tithonia diversifolia",

author = "Wu, \{Tian Shung\} and Shi, \{Li Shian\} and Kuo, \{Ping Chung\} and Leu, \{Yann Lii\} and Liou, \{Meei Jen\} and Wu, \{Pei Lin\} and Wu, \{Yang Chang\} and Iou, \{Song Chou\} and Chen, \{Yuh Pan\} and Chang, \{Hsien Chang\}",

year = "2001",

language = "英语",

volume = "53",

pages = "217--223",

journal = "Chinese Pharmaceutical Journal",

issn = "1016-1015",

publisher = "Chinese Pharmaceutical Association",

number = "5",

}

TY - JOUR

T1 - Cytotoxic principles from the leaves of Tithonia diversifolia

AU - Wu, Tian Shung

AU - Shi, Li Shian

AU - Kuo, Ping Chung

AU - Leu, Yann Lii

AU - Liou, Meei Jen

AU - Wu, Pei Lin

AU - Wu, Yang Chang

AU - Iou, Song Chou

AU - Chen, Yuh Pan

AU - Chang, Hsien Chang

PY - 2001

Y1 - 2001

N2 - Three compounds, acetyltagitinin E (1), tagitinin-F (2) and hispidulin (3), were isolated from the leaves of Tithonia diversifolia. The stereochemistry of 1 was further supported by X-ray crystallography. The cytotoxicity of these compounds was also determined. Compounds 1 and 2 showed selective cytotoxicity to Hep G2 human hepatocellular carcinoma cells.

AB - Three compounds, acetyltagitinin E (1), tagitinin-F (2) and hispidulin (3), were isolated from the leaves of Tithonia diversifolia. The stereochemistry of 1 was further supported by X-ray crystallography. The cytotoxicity of these compounds was also determined. Compounds 1 and 2 showed selective cytotoxicity to Hep G2 human hepatocellular carcinoma cells.

KW - Acetyltagitinin E

KW - Compositae

KW - Sesquiterpene lactone

KW - Tithonia diversifolia

UR - https://www.scopus.com/pages/publications/0035713797

M3 - 文章

AN - SCOPUS:0035713797

SN - 1016-1015

VL - 53

SP - 217

EP - 223

JO - Chinese Pharmaceutical Journal

JF - Chinese Pharmaceutical Journal

IS - 5

ER -

Cytotoxic principles from the leaves of Tithonia diversifolia

摘要

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