Detection of the process of blood coagulation and clot formation using quantitative ultrasonic parameters

Ultrasonic parameters, including attenuation coefficient, sound velocity, and backscattered strength, were applied to detect the process of blood coagulation (BC) and clot formation (CF) in the porcine blood of different hematocrits. Results showed that all three ultrasonic parameters were able to detect the process of BC and CF in which ultrasonic results as a function of time tend to increase largely during the process of BC and to saturate corresponding to the formation of clot. Such results were consistent with the measurement of the blood viscosity as a function of time using a viscometric method.