Development of optical fibre sensors for online pH monitoring in microbioreactors

Min Hsien Wu; Junbo Wang; Jr Lung Lin; Zhanfeng Cui; Zheng Cui

doi:10.1109/NEMS.2007.352140

Development of optical fibre sensors for online pH monitoring in microbioreactors

Min Hsien Wu
, Junbo Wang
, Jr Lung Lin
, Zhanfeng Cui^*
, Zheng Cui^*

^*此作品的通信作者

CCLRC Rutherford Appleton Laboratory
CAS - Institute of Electronics
I-Shou University
University of Oxford

研究成果: 圖書/報告稿件的類型 › 會議稿件 › 同行評審

1 引文斯高帕斯（Scopus）

摘要

The development of non-invasive optical fibre sensor array for on-line monitoring of pH in microbioreactors is described. The working principle is based on the optical absorption of phenol red contained in culture medium. Different from other devices of the similar working principle, the proposed device requires less liquid volume (less than 0.8 μl), is non-invasive, and particularly can be configured as an array. The computer simulation and experimental results revealed that the design of oval detection chamber can substabtially reduce the response time. Also, the system was proved to be able to detect pH change (pH 6.8-7.8) experienced in normal cell culture.

原文	英語
主出版物標題	Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007
頁面	805-808
頁數	4
DOIs	https://doi.org/10.1109/NEMS.2007.352140
出版狀態	已出版 - 2007
對外發佈	是
事件	2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007 - Bangkok, 泰國持續時間: 16 01 2007 → 19 01 2007

出版系列

名字	Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007

Conference

Conference	2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007
國家/地區	泰國
城市	Bangkok
期間	16/01/07 → 19/01/07

存取文件

10.1109/NEMS.2007.352140

其它文件與鏈接

Link to publication in Scopus

引用此

Wu, M. H., Wang, J., Lin, J. L., Cui, Z., & Cui, Z. (2007). Development of optical fibre sensors for online pH monitoring in microbioreactors. 於 Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007 (頁 805-808). 文章 4160443 (Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007). https://doi.org/10.1109/NEMS.2007.352140

Wu, Min Hsien ; Wang, Junbo ; Lin, Jr Lung 等. / Development of optical fibre sensors for online pH monitoring in microbioreactors. Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007. 2007. 頁 805-808 (Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007).

@inproceedings{0359671e8b6243c3bb8ac0b2223b9bd3,

title = "Development of optical fibre sensors for online pH monitoring in microbioreactors",

abstract = "The development of non-invasive optical fibre sensor array for on-line monitoring of pH in microbioreactors is described. The working principle is based on the optical absorption of phenol red contained in culture medium. Different from other devices of the similar working principle, the proposed device requires less liquid volume (less than 0.8 μl), is non-invasive, and particularly can be configured as an array. The computer simulation and experimental results revealed that the design of oval detection chamber can substabtially reduce the response time. Also, the system was proved to be able to detect pH change (pH 6.8-7.8) experienced in normal cell culture.",

author = "Wu, \{Min Hsien\} and Junbo Wang and Lin, \{Jr Lung\} and Zhanfeng Cui and Zheng Cui",

year = "2007",

doi = "10.1109/NEMS.2007.352140",

language = "英语",

isbn = "1424406102",

series = "Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007",

pages = "805--808",

booktitle = "Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007",

note = "2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007 ; Conference date: 16-01-2007 Through 19-01-2007",

}

Wu, MH, Wang, J, Lin, JL, Cui, Z & Cui, Z 2007, Development of optical fibre sensors for online pH monitoring in microbioreactors. 於 Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007., 4160443, Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007, 頁 805-808, 2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007, Bangkok, 泰國, 16/01/07. https://doi.org/10.1109/NEMS.2007.352140

Development of optical fibre sensors for online pH monitoring in microbioreactors. / Wu, Min Hsien; Wang, Junbo; Lin, Jr Lung 等.
Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007. 2007. p. 805-808 4160443 (Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007).

研究成果: 圖書/報告稿件的類型 › 會議稿件 › 同行評審

TY - GEN

T1 - Development of optical fibre sensors for online pH monitoring in microbioreactors

AU - Wu, Min Hsien

AU - Wang, Junbo

AU - Lin, Jr Lung

AU - Cui, Zhanfeng

AU - Cui, Zheng

PY - 2007

Y1 - 2007

N2 - The development of non-invasive optical fibre sensor array for on-line monitoring of pH in microbioreactors is described. The working principle is based on the optical absorption of phenol red contained in culture medium. Different from other devices of the similar working principle, the proposed device requires less liquid volume (less than 0.8 μl), is non-invasive, and particularly can be configured as an array. The computer simulation and experimental results revealed that the design of oval detection chamber can substabtially reduce the response time. Also, the system was proved to be able to detect pH change (pH 6.8-7.8) experienced in normal cell culture.

AB - The development of non-invasive optical fibre sensor array for on-line monitoring of pH in microbioreactors is described. The working principle is based on the optical absorption of phenol red contained in culture medium. Different from other devices of the similar working principle, the proposed device requires less liquid volume (less than 0.8 μl), is non-invasive, and particularly can be configured as an array. The computer simulation and experimental results revealed that the design of oval detection chamber can substabtially reduce the response time. Also, the system was proved to be able to detect pH change (pH 6.8-7.8) experienced in normal cell culture.

UR - https://www.scopus.com/pages/publications/34548135206

U2 - 10.1109/NEMS.2007.352140

DO - 10.1109/NEMS.2007.352140

M3 - 会议稿件

AN - SCOPUS:34548135206

SN - 1424406102

SN - 9781424406104

T3 - Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007

SP - 805

EP - 808

BT - Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007

T2 - 2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007

Y2 - 16 January 2007 through 19 January 2007

ER -

Wu MH, Wang J, Lin JL, Cui Z, Cui Z. Development of optical fibre sensors for online pH monitoring in microbioreactors. 於 Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007. 2007. p. 805-808. 4160443. (Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007). doi: 10.1109/NEMS.2007.352140

Development of optical fibre sensors for online pH monitoring in microbioreactors

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