DNA base-stacking assay utilizing catalytic hairpin assembly-induced gold nanoparticle aggregation for colorimetric protein sensing

Chia Chen Chang; Chie Pein Chen; Chen Yu Chen; Chii Wann Lin

doi:10.1039/c6cc01238h

DNA base-stacking assay utilizing catalytic hairpin assembly-induced gold nanoparticle aggregation for colorimetric protein sensing

Chia Chen Chang
, Chie Pein Chen
, Chen Yu Chen^*
, Chii Wann Lin

^*此作品的通信作者

National Taiwan University
Mackay Memorial Hospital Taiwan

研究成果: 期刊稿件 › 文章 › 同行評審

37 引文斯高帕斯（Scopus）

摘要

A label-free and enzyme-free colorimetric sensing platform for the amplified detection of fibronectin was developed based on an ingenious combination of catalytic hairpin assembly and a base stacking hybridization-based gold nanoparticle aggregation strategy. The detection limit of 2.3 pM is at least one order of magnitude lower than that of established fibronectin biosensors.

原文	英語
頁（從 - 到）	4167-4170
頁數	4
期刊	Chemical Communications
卷	52
發行號	22
DOIs	https://doi.org/10.1039/c6cc01238h
出版狀態	已出版 - 18 03 2016
對外發佈	是

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Publisher Copyright:
© The Royal Society of Chemistry 2016.

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10.1039/c6cc01238h

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title = "DNA base-stacking assay utilizing catalytic hairpin assembly-induced gold nanoparticle aggregation for colorimetric protein sensing",

abstract = "A label-free and enzyme-free colorimetric sensing platform for the amplified detection of fibronectin was developed based on an ingenious combination of catalytic hairpin assembly and a base stacking hybridization-based gold nanoparticle aggregation strategy. The detection limit of 2.3 pM is at least one order of magnitude lower than that of established fibronectin biosensors.",

author = "Chang, \{Chia Chen\} and Chen, \{Chie Pein\} and Chen, \{Chen Yu\} and Lin, \{Chii Wann\}",

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doi = "10.1039/c6cc01238h",

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AU - Chen, Chen Yu

AU - Lin, Chii Wann

PY - 2016/3/18

Y1 - 2016/3/18

N2 - A label-free and enzyme-free colorimetric sensing platform for the amplified detection of fibronectin was developed based on an ingenious combination of catalytic hairpin assembly and a base stacking hybridization-based gold nanoparticle aggregation strategy. The detection limit of 2.3 pM is at least one order of magnitude lower than that of established fibronectin biosensors.

AB - A label-free and enzyme-free colorimetric sensing platform for the amplified detection of fibronectin was developed based on an ingenious combination of catalytic hairpin assembly and a base stacking hybridization-based gold nanoparticle aggregation strategy. The detection limit of 2.3 pM is at least one order of magnitude lower than that of established fibronectin biosensors.

UR - https://www.scopus.com/pages/publications/84960510262

U2 - 10.1039/c6cc01238h

DO - 10.1039/c6cc01238h

M3 - 文章

C2 - 26906691

AN - SCOPUS:84960510262

SN - 1359-7345

VL - 52

SP - 4167

EP - 4170

JO - Chemical Communications

JF - Chemical Communications

IS - 22

ER -

DNA base-stacking assay utilizing catalytic hairpin assembly-induced gold nanoparticle aggregation for colorimetric protein sensing

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