Echinohalimane A, a bioactive halimane-type diterpenoid from a Formosan gorgonian Echinomuricea sp. (plexauridae)

Hsu Ming Chung, Li Chung Hu, Wei Hsuan Yen, Jui Hsin Su, Mei Chin Lu, Tsong Long Hwang, Wei Hsien Wang*, Ping Jyun Sung

*此作品的通信作者

研究成果: 期刊稿件文章同行評審

18 引文 斯高帕斯(Scopus)

摘要

A new halimane-type diterpenoid, echinohalimane A (1), was isolated from a gorgonian, identified as Echinomuricea sp. The structure of 1 was determined by spectroscopic methods and this compound was found to exhibit cytotoxicity toward various tumor cells and display an inhibitory effect on the release of elastase by human neutrophils. Echinohalimane A (1) is the first halimane analogue from the marine organisms belonging to phylum Cnidaria.

原文英語
頁(從 - 到)2246-2253
頁數8
期刊Marine Drugs
10
發行號10
DOIs
出版狀態已出版 - 10 2012

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