Evaluation of the cardiovascular regulatory mechanisms in the medulla oblongata of the rat: low-intensity electrical activation

Samuel H.H. Chan*

*此作品的通信作者

研究成果: 期刊稿件文章同行評審

10 引文 斯高帕斯(Scopus)

摘要

Focal low-intensity (10-20 μA) electrical stimulation in pentobarbital anesthetized rats evoked both hyper- and hypotension from either nucleus reticularis parvocellularis or nucleus reticularis gigantocellularis, the respective representative for classical 'pressor' and 'depressor' areas in the medulla oblongata. The crucial determinants for the degree of such arterial pressure fluctuations appeared to be the pulse frequency and/or intensity of the activating train pulses. It is suggested that neurons responsible for promoting hyper- and hypotension may exist in intermingled populations within each of these two reticular nuclei, and may possess differential sensitivities to the train pulse frequency/current intensity used in electrical stimulation.

原文英語
頁(從 - 到)317-322
頁數6
期刊Journal of the Autonomic Nervous System
11
發行號3
DOIs
出版狀態已出版 - 11 1984
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