Ex vivo study of photothermolysis induced by laser therapy with dynamic optical coherence tomography

Yin Shen Cheng; Tai Ang Wang; Hsiang Chieh Lee; Meng Tsan Tsai

doi:10.1117/12.2674964

Ex vivo study of photothermolysis induced by laser therapy with dynamic optical coherence tomography

Yin Shen Cheng, Tai Ang Wang, Hsiang Chieh Lee, Meng Tsan Tsai^*

^*此作品的通信作者

電機工程學系(含學碩博士班及碩士在職專班)

National Taiwan University

研究成果: 圖書/報告稿件的類型 › 會議稿件 › 同行評審

摘要

In this study, a swept-source optical coherence tomography (SS-OCT) system and a Raman fiber laser with high laser output are used to investigate the photothermal effect on biological tissue. An optical focuser is connected to the Raman fiber laser to focus the laser power on the specific area of the tissue. To simultaneously observe the induced photothermal effect, a dynamic algorithm is used in the process to produce dynamic image of the tissue from time-series OCT images. The results show that with dynamic images, we can identify the extent and area of laser ablation with time. Moreover, after merging the dynamic image and the original OCT image, we can indicate the ablated area in the tissue apart from the surrounding area without ablation.

原文	英語
主出版物標題	Optical Coherence Imaging Techniques and Imaging in Scattering Media V
編輯	Benjamin J. Vakoc, Maciej Wojtkowski, Yoshiaki Yasuno
發行者	SPIE
ISBN（電子）	9781510664739
DOIs	https://doi.org/10.1117/12.2674964
出版狀態	已出版 - 2023
事件	Optical Coherence Imaging Techniques and Imaging in Scattering Media V 2023 - Munich, 德國持續時間: 25 06 2023 → 29 06 2023

出版系列

名字	Proceedings of SPIE - The International Society for Optical Engineering
卷	12632
ISSN（列印）	0277-786X
ISSN（電子）	1996-756X

Conference

Conference	Optical Coherence Imaging Techniques and Imaging in Scattering Media V 2023
國家/地區	德國
城市	Munich
期間	25/06/23 → 29/06/23

文獻附註

Publisher Copyright:
© 2023 SPIE. All rights reserved.

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10.1117/12.2674964

其它文件與鏈接

Link to publication in Scopus

引用此

Cheng, Y. S., Wang, T. A., Lee, H. C., & Tsai, M. T. (2023). Ex vivo study of photothermolysis induced by laser therapy with dynamic optical coherence tomography. 於 B. J. Vakoc, M. Wojtkowski, & Y. Yasuno (編輯), Optical Coherence Imaging Techniques and Imaging in Scattering Media V 文章 1263221 (Proceedings of SPIE - The International Society for Optical Engineering; 卷 12632). SPIE. https://doi.org/10.1117/12.2674964

Cheng, Yin Shen ; Wang, Tai Ang ; Lee, Hsiang Chieh 等. / Ex vivo study of photothermolysis induced by laser therapy with dynamic optical coherence tomography. Optical Coherence Imaging Techniques and Imaging in Scattering Media V. 編輯 / Benjamin J. Vakoc ; Maciej Wojtkowski ; Yoshiaki Yasuno. SPIE, 2023. (Proceedings of SPIE - The International Society for Optical Engineering).

@inproceedings{159b3de5703e4944b86c1a0dd2832b2f,

title = "Ex vivo study of photothermolysis induced by laser therapy with dynamic optical coherence tomography",

abstract = "In this study, a swept-source optical coherence tomography (SS-OCT) system and a Raman fiber laser with high laser output are used to investigate the photothermal effect on biological tissue. An optical focuser is connected to the Raman fiber laser to focus the laser power on the specific area of the tissue. To simultaneously observe the induced photothermal effect, a dynamic algorithm is used in the process to produce dynamic image of the tissue from time-series OCT images. The results show that with dynamic images, we can identify the extent and area of laser ablation with time. Moreover, after merging the dynamic image and the original OCT image, we can indicate the ablated area in the tissue apart from the surrounding area without ablation.",

keywords = "laser therapy, optical coherence tomography, photothermolysis",

author = "Cheng, {Yin Shen} and Wang, {Tai Ang} and Lee, {Hsiang Chieh} and Tsai, {Meng Tsan}",

note = "Publisher Copyright: {\textcopyright} 2023 SPIE. All rights reserved.; Optical Coherence Imaging Techniques and Imaging in Scattering Media V 2023 ; Conference date: 25-06-2023 Through 29-06-2023",

year = "2023",

doi = "10.1117/12.2674964",

language = "英语",

series = "Proceedings of SPIE - The International Society for Optical Engineering",

publisher = "SPIE",

editor = "Vakoc, {Benjamin J.} and Maciej Wojtkowski and Yoshiaki Yasuno",

booktitle = "Optical Coherence Imaging Techniques and Imaging in Scattering Media V",

address = "美国",

}

Cheng, YS, Wang, TA, Lee, HC & Tsai, MT 2023, Ex vivo study of photothermolysis induced by laser therapy with dynamic optical coherence tomography. 於 BJ Vakoc, M Wojtkowski & Y Yasuno (編輯), Optical Coherence Imaging Techniques and Imaging in Scattering Media V., 1263221, Proceedings of SPIE - The International Society for Optical Engineering, 卷 12632, SPIE, Optical Coherence Imaging Techniques and Imaging in Scattering Media V 2023, Munich, 德國, 25/06/23. https://doi.org/10.1117/12.2674964

Ex vivo study of photothermolysis induced by laser therapy with dynamic optical coherence tomography. / Cheng, Yin Shen; Wang, Tai Ang; Lee, Hsiang Chieh 等.
Optical Coherence Imaging Techniques and Imaging in Scattering Media V. 編輯 / Benjamin J. Vakoc; Maciej Wojtkowski; Yoshiaki Yasuno. SPIE, 2023. 1263221 (Proceedings of SPIE - The International Society for Optical Engineering; 卷 12632).

研究成果: 圖書/報告稿件的類型 › 會議稿件 › 同行評審

TY - GEN

T1 - Ex vivo study of photothermolysis induced by laser therapy with dynamic optical coherence tomography

AU - Cheng, Yin Shen

AU - Wang, Tai Ang

AU - Lee, Hsiang Chieh

AU - Tsai, Meng Tsan

PY - 2023

Y1 - 2023

N2 - In this study, a swept-source optical coherence tomography (SS-OCT) system and a Raman fiber laser with high laser output are used to investigate the photothermal effect on biological tissue. An optical focuser is connected to the Raman fiber laser to focus the laser power on the specific area of the tissue. To simultaneously observe the induced photothermal effect, a dynamic algorithm is used in the process to produce dynamic image of the tissue from time-series OCT images. The results show that with dynamic images, we can identify the extent and area of laser ablation with time. Moreover, after merging the dynamic image and the original OCT image, we can indicate the ablated area in the tissue apart from the surrounding area without ablation.

AB - In this study, a swept-source optical coherence tomography (SS-OCT) system and a Raman fiber laser with high laser output are used to investigate the photothermal effect on biological tissue. An optical focuser is connected to the Raman fiber laser to focus the laser power on the specific area of the tissue. To simultaneously observe the induced photothermal effect, a dynamic algorithm is used in the process to produce dynamic image of the tissue from time-series OCT images. The results show that with dynamic images, we can identify the extent and area of laser ablation with time. Moreover, after merging the dynamic image and the original OCT image, we can indicate the ablated area in the tissue apart from the surrounding area without ablation.

KW - laser therapy

KW - optical coherence tomography

KW - photothermolysis

UR - http://www.scopus.com/inward/record.url?scp=85172861154&partnerID=8YFLogxK

U2 - 10.1117/12.2674964

DO - 10.1117/12.2674964

M3 - 会议稿件

AN - SCOPUS:85172861154

T3 - Proceedings of SPIE - The International Society for Optical Engineering

BT - Optical Coherence Imaging Techniques and Imaging in Scattering Media V

A2 - Vakoc, Benjamin J.

A2 - Wojtkowski, Maciej

A2 - Yasuno, Yoshiaki

PB - SPIE

T2 - Optical Coherence Imaging Techniques and Imaging in Scattering Media V 2023

Y2 - 25 June 2023 through 29 June 2023

ER -

Cheng YS, Wang TA, Lee HC, Tsai MT. Ex vivo study of photothermolysis induced by laser therapy with dynamic optical coherence tomography. 於 Vakoc BJ, Wojtkowski M, Yasuno Y, 編輯, Optical Coherence Imaging Techniques and Imaging in Scattering Media V. SPIE. 2023. 1263221. (Proceedings of SPIE - The International Society for Optical Engineering). doi: 10.1117/12.2674964

Ex vivo study of photothermolysis induced by laser therapy with dynamic optical coherence tomography

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