F4/80 and the related adhesion-GPCRs

Siamon Gordon*, Jörg Hamann, Hsi Hsien Lin, Martin Stacey

*此作品的通信作者

研究成果: 期刊稿件評論/辯論

120 引文 斯高帕斯(Scopus)

摘要

The F4/80 monoclonal antibody was first reported in this journal 30 years ago (Eur. J. Immunol. 1981. 11: 805-815). F4/80 has become a widely used marker for monocytes and many, but not all, tissue macrophages in the mouse. F4/80 is a member of the EGF-TM7 family of leukocyte plasma membrane heptahelical molecules, which includes CD97 and EMR2. This Viewpoint summarises current knowledge of the expression, structure and functions of the EGF-TM7 family, as part of a larger family of tissue adhesion-GPCRs.

原文英語
頁(從 - 到)2472-2476
頁數5
期刊European Journal of Immunology
41
發行號9
DOIs
出版狀態已出版 - 09 2011

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