摘要
The F4/80 monoclonal antibody was first reported in this journal 30 years ago (Eur. J. Immunol. 1981. 11: 805-815). F4/80 has become a widely used marker for monocytes and many, but not all, tissue macrophages in the mouse. F4/80 is a member of the EGF-TM7 family of leukocyte plasma membrane heptahelical molecules, which includes CD97 and EMR2. This Viewpoint summarises current knowledge of the expression, structure and functions of the EGF-TM7 family, as part of a larger family of tissue adhesion-GPCRs.
原文 | 英語 |
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頁(從 - 到) | 2472-2476 |
頁數 | 5 |
期刊 | European Journal of Immunology |
卷 | 41 |
發行號 | 9 |
DOIs |
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出版狀態 | 已出版 - 09 2011 |