Hedyotis diffusa combined with scutellaria barbata are the core treatment of Chinese herbal medicine used for breast cancer patients: A population-based study

Yuan Chieh Yeh, Hsing Yu Chen, Sien Hung Yang, Yi Hsien Lin, Jen Hwey Chiu, Yi Hsuan Lin, Jiun Liang Chen*

*此作品的通信作者

研究成果: 期刊稿件文章同行評審

61 引文 斯高帕斯(Scopus)

摘要

Traditional Chinese medicine (TCM), which is the most common type of complementary and alternative medicine (CAM) used in Taiwan, is increasingly used to treat patients with breast cancer. However, large-scale studies on the patterns of TCM prescriptions for breast cancer are still lacking. The aim of this study was to determine the core treatment of TCM prescriptions used for breast cancer recorded in the Taiwan National Health Insurance Research Database. TCM visits made for breast cancer in 2008 were identified using ICD-9 codes. The prescriptions obtained at these TCM visits were evaluated using association rule mining to evaluate the combinations of Chinese herbal medicine (CHM) used to treat breast cancer patients. A total of 37,176 prescriptions were made for 4,436 outpatients with breast cancer. Association rule mining and network analysis identified Hedyotis diffusa plus Scutellaria barbata as the most common duplex medicinal (10.9%) used for the core treatment of breast cancer. Jia-Wei-Xiao-Yao-San (19.6%) and Hedyotis diffusa (41.9%) were the most commonly prescribed herbal formula (HF) and single herb (SH), respectively. Only 35% of the commonly used CHM had been studied for efficacy. More clinical trials are needed to evaluate the efficacy and safety of these CHM used to treat breast cancer.

原文英語
文章編號202378
期刊Evidence-based Complementary and Alternative Medicine
2014
DOIs
出版狀態已出版 - 2014

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