In vivo skin imaging and laser therapy observation with ultrahigh-resolution optical coherence tomography

Tai Ang Wang; Yin Shen Cheng; Hsiang Chieh Lee; Chau Yee Ng; Meng Tsan Tsai

doi:10.1117/12.2670560

In vivo skin imaging and laser therapy observation with ultrahigh-resolution optical coherence tomography

Tai Ang Wang, Yin Shen Cheng, Hsiang Chieh Lee, Chau Yee Ng, Meng Tsan Tsai^*

^*此作品的通信作者

電機工程學系(含學碩博士班及碩士在職專班)

研究成果: 圖書/報告稿件的類型 › 會議稿件 › 同行評審

摘要

The diagnosis and treatment of dermatological diseases has always been valued, and the laser therapy is one of the main methods for the treatment of skin diseases. Optical coherence tomography (OCT) is a non-invasive, label-free, high-resolution and high-speed imaging technique, which is very suitable as a diagnostic tool in dermatology. In this study, we developed an ultrahigh-resolution OCT system (UHR-OCT), with below 2 µm in both axial and lateral resolution in tissue. The system is implemented to observe skin microstructure and layering, and to investigate postoperative follow-up of laser therapy. The results show that the developed UHR-OCT system can clearly distinguish the microstructure and layering of the skin, meaning that the system is well-suitable for skin diagnosis. In addition, we also investigated the photodamage such as LIOB in the tracking of laser treatment, which confirmed the value of UHR-OCT system in dermatology and laser treatment.

原文	英語
主出版物標題	Optical Coherence Imaging Techniques and Imaging in Scattering Media V
編輯	Benjamin J. Vakoc, Maciej Wojtkowski, Yoshiaki Yasuno
發行者	SPIE
ISBN（電子）	9781510664739
DOIs	https://doi.org/10.1117/12.2670560
出版狀態	已出版 - 2023
事件	Optical Coherence Imaging Techniques and Imaging in Scattering Media V 2023 - Munich, 德國持續時間: 25 06 2023 → 29 06 2023

出版系列

名字	Proceedings of SPIE - The International Society for Optical Engineering
卷	12632
ISSN（列印）	0277-786X
ISSN（電子）	1996-756X

Conference

Conference	Optical Coherence Imaging Techniques and Imaging in Scattering Media V 2023
國家/地區	德國
城市	Munich
期間	25/06/23 → 29/06/23

文獻附註

Publisher Copyright:
© 2023 SPIE. All rights reserved.

存取文件

10.1117/12.2670560

其它文件與鏈接

Link to publication in Scopus

引用此

Wang, T. A., Cheng, Y. S., Lee, H. C., Ng, C. Y., & Tsai, M. T. (2023). In vivo skin imaging and laser therapy observation with ultrahigh-resolution optical coherence tomography. 於 B. J. Vakoc, M. Wojtkowski, & Y. Yasuno (編輯), Optical Coherence Imaging Techniques and Imaging in Scattering Media V 文章 1263225 (Proceedings of SPIE - The International Society for Optical Engineering; 卷 12632). SPIE. https://doi.org/10.1117/12.2670560

Wang, Tai Ang ; Cheng, Yin Shen ; Lee, Hsiang Chieh 等. / In vivo skin imaging and laser therapy observation with ultrahigh-resolution optical coherence tomography. Optical Coherence Imaging Techniques and Imaging in Scattering Media V. 編輯 / Benjamin J. Vakoc ; Maciej Wojtkowski ; Yoshiaki Yasuno. SPIE, 2023. (Proceedings of SPIE - The International Society for Optical Engineering).

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title = "In vivo skin imaging and laser therapy observation with ultrahigh-resolution optical coherence tomography",

abstract = "The diagnosis and treatment of dermatological diseases has always been valued, and the laser therapy is one of the main methods for the treatment of skin diseases. Optical coherence tomography (OCT) is a non-invasive, label-free, high-resolution and high-speed imaging technique, which is very suitable as a diagnostic tool in dermatology. In this study, we developed an ultrahigh-resolution OCT system (UHR-OCT), with below 2 µm in both axial and lateral resolution in tissue. The system is implemented to observe skin microstructure and layering, and to investigate postoperative follow-up of laser therapy. The results show that the developed UHR-OCT system can clearly distinguish the microstructure and layering of the skin, meaning that the system is well-suitable for skin diagnosis. In addition, we also investigated the photodamage such as LIOB in the tracking of laser treatment, which confirmed the value of UHR-OCT system in dermatology and laser treatment.",

keywords = "disease, laser treatment, skin, ultrahigh-resolution optical coherence tomography",

author = "Wang, {Tai Ang} and Cheng, {Yin Shen} and Lee, {Hsiang Chieh} and Ng, {Chau Yee} and Tsai, {Meng Tsan}",

note = "Publisher Copyright: {\textcopyright} 2023 SPIE. All rights reserved.; Optical Coherence Imaging Techniques and Imaging in Scattering Media V 2023 ; Conference date: 25-06-2023 Through 29-06-2023",

year = "2023",

doi = "10.1117/12.2670560",

language = "英语",

series = "Proceedings of SPIE - The International Society for Optical Engineering",

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Wang, TA, Cheng, YS, Lee, HC, Ng, CY & Tsai, MT 2023, In vivo skin imaging and laser therapy observation with ultrahigh-resolution optical coherence tomography. 於 BJ Vakoc, M Wojtkowski & Y Yasuno (編輯), Optical Coherence Imaging Techniques and Imaging in Scattering Media V., 1263225, Proceedings of SPIE - The International Society for Optical Engineering, 卷 12632, SPIE, Optical Coherence Imaging Techniques and Imaging in Scattering Media V 2023, Munich, 德國, 25/06/23. https://doi.org/10.1117/12.2670560

In vivo skin imaging and laser therapy observation with ultrahigh-resolution optical coherence tomography. / Wang, Tai Ang; Cheng, Yin Shen; Lee, Hsiang Chieh 等.
Optical Coherence Imaging Techniques and Imaging in Scattering Media V. 編輯 / Benjamin J. Vakoc; Maciej Wojtkowski; Yoshiaki Yasuno. SPIE, 2023. 1263225 (Proceedings of SPIE - The International Society for Optical Engineering; 卷 12632).

研究成果: 圖書/報告稿件的類型 › 會議稿件 › 同行評審

TY - GEN

T1 - In vivo skin imaging and laser therapy observation with ultrahigh-resolution optical coherence tomography

AU - Wang, Tai Ang

AU - Cheng, Yin Shen

AU - Lee, Hsiang Chieh

AU - Ng, Chau Yee

AU - Tsai, Meng Tsan

PY - 2023

Y1 - 2023

N2 - The diagnosis and treatment of dermatological diseases has always been valued, and the laser therapy is one of the main methods for the treatment of skin diseases. Optical coherence tomography (OCT) is a non-invasive, label-free, high-resolution and high-speed imaging technique, which is very suitable as a diagnostic tool in dermatology. In this study, we developed an ultrahigh-resolution OCT system (UHR-OCT), with below 2 µm in both axial and lateral resolution in tissue. The system is implemented to observe skin microstructure and layering, and to investigate postoperative follow-up of laser therapy. The results show that the developed UHR-OCT system can clearly distinguish the microstructure and layering of the skin, meaning that the system is well-suitable for skin diagnosis. In addition, we also investigated the photodamage such as LIOB in the tracking of laser treatment, which confirmed the value of UHR-OCT system in dermatology and laser treatment.

AB - The diagnosis and treatment of dermatological diseases has always been valued, and the laser therapy is one of the main methods for the treatment of skin diseases. Optical coherence tomography (OCT) is a non-invasive, label-free, high-resolution and high-speed imaging technique, which is very suitable as a diagnostic tool in dermatology. In this study, we developed an ultrahigh-resolution OCT system (UHR-OCT), with below 2 µm in both axial and lateral resolution in tissue. The system is implemented to observe skin microstructure and layering, and to investigate postoperative follow-up of laser therapy. The results show that the developed UHR-OCT system can clearly distinguish the microstructure and layering of the skin, meaning that the system is well-suitable for skin diagnosis. In addition, we also investigated the photodamage such as LIOB in the tracking of laser treatment, which confirmed the value of UHR-OCT system in dermatology and laser treatment.

KW - disease

KW - laser treatment

KW - skin

KW - ultrahigh-resolution optical coherence tomography

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DO - 10.1117/12.2670560

M3 - 会议稿件

AN - SCOPUS:85172911213

T3 - Proceedings of SPIE - The International Society for Optical Engineering

BT - Optical Coherence Imaging Techniques and Imaging in Scattering Media V

A2 - Vakoc, Benjamin J.

A2 - Wojtkowski, Maciej

A2 - Yasuno, Yoshiaki

PB - SPIE

T2 - Optical Coherence Imaging Techniques and Imaging in Scattering Media V 2023

Y2 - 25 June 2023 through 29 June 2023

ER -

Wang TA, Cheng YS, Lee HC, Ng CY, Tsai MT. In vivo skin imaging and laser therapy observation with ultrahigh-resolution optical coherence tomography. 於 Vakoc BJ, Wojtkowski M, Yasuno Y, 編輯, Optical Coherence Imaging Techniques and Imaging in Scattering Media V. SPIE. 2023. 1263225. (Proceedings of SPIE - The International Society for Optical Engineering). doi: 10.1117/12.2670560

In vivo skin imaging and laser therapy observation with ultrahigh-resolution optical coherence tomography

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