TY - JOUR
T1 - Intraepidermal neutrophilic IgA dermatosis
AU - Kuan, Yue Zon
AU - Chiou, Horng Tsann
AU - Chang, Hui Ching
AU - Chan, Heng Leong
AU - Kuo, Tseng tong
PY - 1990
Y1 - 1990
N2 - We report a patient with a vesiculopustular eruption with features distinct from typical subcorneal pustular dermatosis. Clinically, well-formed pustular lesions, which were flowerlike in appearance, were present. Histopathologically, early vesicular lesions showed intraepidermal bullae containing numerous neutrophils, a few eosinophils, and acanthc-lytic cells. Direct immunofluorescence study revealed IgA deposits in the intercellular space of the epidermis. The patient's serum, however, did not contain circulating antibodies reactive with the epidermis. We consider this eruption an immunologically mediated, intraepidermal blistering disease, similar to intraepidermal neutrophilic IgA dermatosis.
AB - We report a patient with a vesiculopustular eruption with features distinct from typical subcorneal pustular dermatosis. Clinically, well-formed pustular lesions, which were flowerlike in appearance, were present. Histopathologically, early vesicular lesions showed intraepidermal bullae containing numerous neutrophils, a few eosinophils, and acanthc-lytic cells. Direct immunofluorescence study revealed IgA deposits in the intercellular space of the epidermis. The patient's serum, however, did not contain circulating antibodies reactive with the epidermis. We consider this eruption an immunologically mediated, intraepidermal blistering disease, similar to intraepidermal neutrophilic IgA dermatosis.
UR - https://www.scopus.com/pages/publications/0025423213
U2 - 10.1016/0190-9622(90)70125-2
DO - 10.1016/0190-9622(90)70125-2
M3 - 文章
C2 - 2186060
AN - SCOPUS:0025423213
SN - 0190-9622
VL - 22
SP - 917
EP - 919
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
IS - 5
ER -