摘要
Chronic hepatitis B virus (HBV) infection is a major global health problem. Current antiviral therapy including pegylated interferon and nucleos(t)ide analogue is effective in reducing progression to cirrhosis, hepatic decompensation, and hepatocellular carcinoma but the rate of HBsAg seroclearance is low. In this chapter, we review the barriers to eradicate HBV and how they may be overcome. We also discuss how cure of chronic HBV infection should be defined and measured and the likelihood that new antiviral and immune-modulatory drugs in development can achieve the goal of HBV cure.
| 原文 | 英語 |
|---|---|
| 主出版物標題 | Hepatitis B Virus and Liver Disease |
| 發行者 | Springer Nature |
| 頁面 | 475-495 |
| 頁數 | 21 |
| ISBN（電子） | 9789811636158 |
| ISBN（列印） | 9789811636141 |
| DOIs | |
| 出版狀態 | 已出版 - 23 08 2021 |
文獻附註
Publisher Copyright:© The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2021. All rights reserved.
UN SDG
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SDG3 健康與福祉
指紋
深入研究「Is cure of hepatitis B infection a mission possible?」主題。共同形成了獨特的指紋。引用此
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