L&H variants of Reed-Sternberg cells express sialylated Leu M1 antigen

S. M. Hsu, Y. S. Ho, P. J. Li, J. Monheit, H. J. Ree, K. Sheibani, C. D. Winberg

研究成果: 期刊稿件文章同行評審

31 引文 斯高帕斯(Scopus)

摘要

Anti-Leu M1 generally does not stain the lymphocytic and histiocytic (L&H) variants of Reed-Sternberg cells in the lymphocyte predominant type of Hodgkin's disease. however, the authors found that after neuraminidase treatment for removal of sialic acid, the L&H cells in more than half of the cases studied could be stained by anti-Leu M1. This result strongly suggests that L&H cells differ from the Reed-Sternberg cells in other types of Hodgkin's disease in their unique capacity to sialylate the 150-kd Leu M1 antigen.

原文英語
頁(從 - 到)199-203
頁數5
期刊American Journal of Pathology
122
發行號2
出版狀態已出版 - 1986
對外發佈

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