Long-Term Outcomes After Thoracoscopic Resection of Stage I and II Thymoma: A Propensity-Matched Study

Yin Kai Chao, Yun Hen Liu, Ming Ju Hsieh, Yi Cheng Wu, Tzu Ping Chen, Ming Shian Lu, Hung I. Lu, Hui Ping Liu*

*此作品的通信作者

研究成果: 期刊稿件文章同行評審

22 引文 斯高帕斯(Scopus)

摘要

Purpose: The use of video-assisted thoracoscopic surgery (VATS) in patients with thymoma remains controversial. We sought to evaluate the perioperative and oncological outcomes after VATS resection for stage I and II thymoma and to compare the outcomes with those obtained after median sternotomy (MST). Methods: Between 1991 and 2007, a total of 140 patients with stage I and II thymoma underwent surgery at the Chang Gung Memorial Hospital. Of them, 58 underwent MST, 61 VATS, and 21 thoracotomy. Using a propensity score based on four variables (myasthenia gravis, tumor size on CT images, age, and Masaoka stage), 48 VATS-treated patients were matched to 48 patients who received MST. Outcomes compared included perioperative complications, length of stay, tumor recurrence, and survival. Results: No operative deaths occurred in this study. VATS was associated with fewer intraoperative blood loss, and more patients in the VATS group were extubated in the operating room after surgery compared with the MST group (37.5 vs. 12.5 %, respectively, P = 0.005). The mean length of stay was shorter in the VATS group than in the MST group (5.8 vs. 7 days, respectively; P = 0.008). After a median follow-up of 53 months, five patients developed recurrent tumors (four pleural and one pericardial). No statistically significant differences were found in the 5-year survival rates between the two study groups. Conclusions: VATS appears feasible for patients with stage I and II thymoma and is associated with better perioperative outcomes than MST. The oncological outcomes are also similar.

原文英語
頁(從 - 到)1371-1376
頁數6
期刊Annals of Surgical Oncology
22
發行號4
DOIs
出版狀態已出版 - 01 03 2015
對外發佈

文獻附註

Publisher Copyright:
© 2014, Society of Surgical Oncology.

指紋

深入研究「Long-Term Outcomes After Thoracoscopic Resection of Stage I and II Thymoma: A Propensity-Matched Study」主題。共同形成了獨特的指紋。

引用此