Medication compliance and clinical outcomes of fixed-dose combinations vs free combinations of an angiotensin II receptor blocker and a calcium channel blocker in hypertension treatment

Ying Chang Tung; Yu Chang Huang; Lung Sheng Wu; Chee Jen Chang; Pao Hsien Chu

doi:10.1111/jch.13035

Medication compliance and clinical outcomes of fixed-dose combinations vs free combinations of an angiotensin II receptor blocker and a calcium channel blocker in hypertension treatment

Ying Chang Tung, Yu Chang Huang, Lung Sheng Wu, Chee Jen Chang, Pao Hsien Chu^*

^*此作品的通信作者

人工智慧學系(含學碩博士班)

Chang Gung University

研究成果: 期刊稿件 › 文章 › 同行評審

14 引文斯高帕斯（Scopus）

摘要

Using the National Health Insurance Research Database of Taiwan, the authors identified 1136 patients taking fixed-dose combination and 4544 patients taking free combinations of an angiotensin II receptor blocker and a dihydropyridine calcium channel blocker from January 2009 to December 2012. At a mean follow-up of 2.1 years, the fixed-dose combination was associated with improved medication adherence and persistence and better survival free from major adverse cardiac events and hospitalization for heart failure compared with the free combination regimens.

原文	英語
頁（從 - 到）	983-989
頁數	7
期刊	Journal of Clinical Hypertension
卷	19
發行號	10
DOIs	https://doi.org/10.1111/jch.13035
出版狀態	已出版 - 10 2017

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©2017 Wiley Periodicals, Inc.

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10.1111/jch.13035

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title = "Medication compliance and clinical outcomes of fixed-dose combinations vs free combinations of an angiotensin II receptor blocker and a calcium channel blocker in hypertension treatment",

abstract = "Using the National Health Insurance Research Database of Taiwan, the authors identified 1136 patients taking fixed-dose combination and 4544 patients taking free combinations of an angiotensin II receptor blocker and a dihydropyridine calcium channel blocker from January 2009 to December 2012. At a mean follow-up of 2.1 years, the fixed-dose combination was associated with improved medication adherence and persistence and better survival free from major adverse cardiac events and hospitalization for heart failure compared with the free combination regimens.",

keywords = "angiotensin II receptor blocker, dihydropyridine calcium channel blocker, fixed-dose combination, hypertension, major adverse cardiac event",

author = "Tung, {Ying Chang} and Huang, {Yu Chang} and Wu, {Lung Sheng} and Chang, {Chee Jen} and Chu, {Pao Hsien}",

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year = "2017",

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doi = "10.1111/jch.13035",

language = "英语",

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Medication compliance and clinical outcomes of fixed-dose combinations vs free combinations of an angiotensin II receptor blocker and a calcium channel blocker in hypertension treatment. / Tung, Ying Chang; Huang, Yu Chang; Wu, Lung Sheng 等.
於: Journal of Clinical Hypertension, 卷 19, 編號 10, 10.2017, p. 983-989.

研究成果: 期刊稿件 › 文章 › 同行評審

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T1 - Medication compliance and clinical outcomes of fixed-dose combinations vs free combinations of an angiotensin II receptor blocker and a calcium channel blocker in hypertension treatment

AU - Tung, Ying Chang

AU - Huang, Yu Chang

AU - Wu, Lung Sheng

AU - Chang, Chee Jen

AU - Chu, Pao Hsien

PY - 2017/10

Y1 - 2017/10

N2 - Using the National Health Insurance Research Database of Taiwan, the authors identified 1136 patients taking fixed-dose combination and 4544 patients taking free combinations of an angiotensin II receptor blocker and a dihydropyridine calcium channel blocker from January 2009 to December 2012. At a mean follow-up of 2.1 years, the fixed-dose combination was associated with improved medication adherence and persistence and better survival free from major adverse cardiac events and hospitalization for heart failure compared with the free combination regimens.

AB - Using the National Health Insurance Research Database of Taiwan, the authors identified 1136 patients taking fixed-dose combination and 4544 patients taking free combinations of an angiotensin II receptor blocker and a dihydropyridine calcium channel blocker from January 2009 to December 2012. At a mean follow-up of 2.1 years, the fixed-dose combination was associated with improved medication adherence and persistence and better survival free from major adverse cardiac events and hospitalization for heart failure compared with the free combination regimens.

KW - angiotensin II receptor blocker

KW - dihydropyridine calcium channel blocker

KW - fixed-dose combination

KW - hypertension

KW - major adverse cardiac event

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U2 - 10.1111/jch.13035

DO - 10.1111/jch.13035

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SN - 1524-6175

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JO - Journal of Clinical Hypertension

JF - Journal of Clinical Hypertension

IS - 10

ER -

Medication compliance and clinical outcomes of fixed-dose combinations vs free combinations of an angiotensin II receptor blocker and a calcium channel blocker in hypertension treatment

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