Microfluidic impedance flow cytometry enabling high-throughput single-cell electrical property characterization

Jian Chen; Chengcheng Xue; Yang Zhao; Deyong Chen; Min Hsien Wu; Junbo Wang

doi:10.3390/ijms16059804

Microfluidic impedance flow cytometry enabling high-throughput single-cell electrical property characterization

Jian Chen
, Chengcheng Xue
, Yang Zhao
, Deyong Chen
, Min Hsien Wu^*
, Junbo Wang

^*此作品的通信作者

生物醫學工程學系(含學碩博士班)

CAS - Institute of Electronics

研究成果: 期刊稿件 › 文獻綜述 › 同行評審

147 引文斯高帕斯（Scopus）

摘要

This article reviews recent developments in microfluidic impedance flow cytometry for high-throughput electrical property characterization of single cells. Four major perspectives of microfluidic impedance flow cytometry for single-cell characterization are included in this review: (1) early developments of microfluidic impedance flow cytometry for single-cell electrical property characterization; (2) microfluidic impedance flow cytometry with enhanced sensitivity; (3) microfluidic impedance and optical flow cytometry for single-cell analysis and (4) integrated point of care system based on microfluidic impedance flow cytometry. We examine the advantages and limitations of each technique and discuss future research opportunities from the perspectives of both technical innovation and clinical applications.

原文	英語
頁（從 - 到）	9804-9830
頁數	27
期刊	International Journal of Molecular Sciences
卷	16
發行號	5
DOIs	https://doi.org/10.3390/ijms16059804
出版狀態	已出版 - 29 04 2015

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Publisher Copyright:
© 2015 by the authors; licensee MDPI, Basel, Switzerland.

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10.3390/ijms16059804

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title = "Microfluidic impedance flow cytometry enabling high-throughput single-cell electrical property characterization",

abstract = "This article reviews recent developments in microfluidic impedance flow cytometry for high-throughput electrical property characterization of single cells. Four major perspectives of microfluidic impedance flow cytometry for single-cell characterization are included in this review: (1) early developments of microfluidic impedance flow cytometry for single-cell electrical property characterization; (2) microfluidic impedance flow cytometry with enhanced sensitivity; (3) microfluidic impedance and optical flow cytometry for single-cell analysis and (4) integrated point of care system based on microfluidic impedance flow cytometry. We examine the advantages and limitations of each technique and discuss future research opportunities from the perspectives of both technical innovation and clinical applications.",

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author = "Jian Chen and Chengcheng Xue and Yang Zhao and Deyong Chen and Wu, \{Min Hsien\} and Junbo Wang",

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AU - Chen, Jian

AU - Xue, Chengcheng

AU - Zhao, Yang

AU - Chen, Deyong

AU - Wu, Min Hsien

AU - Wang, Junbo

PY - 2015/4/29

Y1 - 2015/4/29

N2 - This article reviews recent developments in microfluidic impedance flow cytometry for high-throughput electrical property characterization of single cells. Four major perspectives of microfluidic impedance flow cytometry for single-cell characterization are included in this review: (1) early developments of microfluidic impedance flow cytometry for single-cell electrical property characterization; (2) microfluidic impedance flow cytometry with enhanced sensitivity; (3) microfluidic impedance and optical flow cytometry for single-cell analysis and (4) integrated point of care system based on microfluidic impedance flow cytometry. We examine the advantages and limitations of each technique and discuss future research opportunities from the perspectives of both technical innovation and clinical applications.

AB - This article reviews recent developments in microfluidic impedance flow cytometry for high-throughput electrical property characterization of single cells. Four major perspectives of microfluidic impedance flow cytometry for single-cell characterization are included in this review: (1) early developments of microfluidic impedance flow cytometry for single-cell electrical property characterization; (2) microfluidic impedance flow cytometry with enhanced sensitivity; (3) microfluidic impedance and optical flow cytometry for single-cell analysis and (4) integrated point of care system based on microfluidic impedance flow cytometry. We examine the advantages and limitations of each technique and discuss future research opportunities from the perspectives of both technical innovation and clinical applications.

KW - High throughput

KW - Impedance flow cytometry

KW - Microfluidics

KW - Single-cell electrical property analysis

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DO - 10.3390/ijms16059804

M3 - 文献综述

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AN - SCOPUS:84929340112

SN - 1661-6596

VL - 16

SP - 9804

EP - 9830

JO - International Journal of Molecular Sciences

JF - International Journal of Molecular Sciences

IS - 5

ER -

Microfluidic impedance flow cytometry enabling high-throughput single-cell electrical property characterization

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