Nasopharyngeal carcinoma in children: A single institution's experience

Jiunn Ming Sheen, Hong Ren Yu, Eng Yen Huang, Kuan Sheng Wu, Shiou Huei Wei, Chih Cheng Hsiao*

*此作品的通信作者

研究成果: 期刊稿件文章同行評審

2 引文 斯高帕斯(Scopus)

摘要

Nasopharyngeal carcinoma is a very rare disease of children. Between 1992 and 2005, 8 male and 2 female patients [ages ranging from 12 to 17 years,] were treated in our institution. The histopathologies were all undifferentiated type (WHO Type III). Of the ten patients, one was T2, five were T3, and four were T4, respectively (TNM system of the American Joint Committee for Cancer Staging). Eight patients had node metastases, 6/8 had bilateral and 4/8 had nodes larger than 6 cm. The main symptoms at diagnosis were neck mass followed by nasal, aural symptoms, cranial nerve palsy and headache. Four patients received radiotherapy only, while six patients received cisplatin-based concomitant chemoradiotherapy. The mean irradiation doses to the primary sites were 7200 cGy. Two patients developed early systemic relapse and died one year and 4 months, respectively, after relapse. After a median follow-up of 30 months, the event-free survival and overall survival were 70% and 75%, respectively. Although the sample size was small, it seemed that the patients had a good chance of survival in spite of advanced stage. However, late morbidity was a concern.

原文英語
頁(從 - 到)268-271+328
期刊Zhonghua Minguo xiao er ke yi xue hui za zhi [Journal]. Zhonghua Minguo xiao er ke yi xue hui
46
發行號5
出版狀態已出版 - 09 2005
對外發佈

指紋

深入研究「Nasopharyngeal carcinoma in children: A single institution's experience」主題。共同形成了獨特的指紋。

引用此