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New polyoxygenated briaranes from octocorals briareum excavatum and ellisella robusta

  • Tsong Long Hwang
  • , Mei Ru Lin
  • , Wei Tse Tsai
  • , Hsiao Chien Yeh
  • , Wan Ping Hu
  • , Jyh Horng Sheu
  • , Ping Jyun Sung*
  • *此作品的通信作者
  • National Museum of Marine Biology and Aquarium, Taiwan
  • National Sun Yat-sen University
  • National Dong Hwa University
  • Kaohsiung Medical University

研究成果: 期刊稿件文章同行評審

31 引文 斯高帕斯(Scopus)

摘要

Six new polyoxygenated briarane-type diterpenoids, briaexcavatins Q-T (1-4) and robustolides J (5) and K (6), were isolated from a cultured octocoral Briareum excavation and a sea whip gorgonian coral Ellisella robusta, respectively. The structures of briaranes 1-6 were established by spectroscopic methods. Briarane 3 exhibited weak cytotoxicity toward CCRF-CEM tumor cells and briaranes 5 and 6 displayed inhibitory effects on superoxide anion generation by human neutrophils.

原文英語
頁(從 - 到)1638-1646
頁數9
期刊Bulletin of the Chemical Society of Japan
81
發行號12
DOIs
出版狀態已出版 - 2008

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