Oxidative trimerization of indoles via water-assisted visible-light photoredox catalysis and the study of their anti-cancer activities

Li Ting Cheng, Sheng Qi Luo, Bor Cherng Hong*, Chia Ling Chen, Wen Shan Li*, Gene Hsiang Lee

*此作品的通信作者

研究成果: 期刊稿件文章同行評審

10 引文 斯高帕斯(Scopus)

摘要

Incorporation of water has been revealed to successfully facilitate visible-light photoredox catalysis of indole leading to increased production of C2-quaternary indolinone. The water-promoted photoreaction of indole under catalyst-free conditions by a household compact fluorescence light was also demonstrated. The antiproliferative activity of the synthesized indolinones was evaluated against three human cancer cell lines.

原文英語
頁(從 - 到)6247-6252
頁數6
期刊Organic and Biomolecular Chemistry
18
發行號32
DOIs
出版狀態已出版 - 28 08 2020
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Publisher Copyright:
© 2020 The Royal Society of Chemistry.

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