Oxidative trimerization of indoles via water-assisted visible-light photoredox catalysis and the study of their anti-cancer activities

Li Ting Cheng; Sheng Qi Luo; Bor Cherng Hong; Chia Ling Chen; Wen Shan Li; Gene Hsiang Lee

doi:10.1039/d0ob01298j

Oxidative trimerization of indoles via water-assisted visible-light photoredox catalysis and the study of their anti-cancer activities

Li Ting Cheng, Sheng Qi Luo, Bor Cherng Hong^*, Chia Ling Chen, Wen Shan Li^*, Gene Hsiang Lee

^*此作品的通信作者

研究成果: 期刊稿件 › 文章 › 同行評審

14 引文斯高帕斯（Scopus）

摘要

Incorporation of water has been revealed to successfully facilitate visible-light photoredox catalysis of indole leading to increased production of C2-quaternary indolinone. The water-promoted photoreaction of indole under catalyst-free conditions by a household compact fluorescence light was also demonstrated. The antiproliferative activity of the synthesized indolinones was evaluated against three human cancer cell lines.

原文	英語
頁（從 - 到）	6247-6252
頁數	6
期刊	Organic and Biomolecular Chemistry
卷	18
發行號	32
DOIs	https://doi.org/10.1039/d0ob01298j
出版狀態	已出版 - 28 08 2020
對外發佈	是

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© 2020 The Royal Society of Chemistry.

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title = "Oxidative trimerization of indoles via water-assisted visible-light photoredox catalysis and the study of their anti-cancer activities",

abstract = "Incorporation of water has been revealed to successfully facilitate visible-light photoredox catalysis of indole leading to increased production of C2-quaternary indolinone. The water-promoted photoreaction of indole under catalyst-free conditions by a household compact fluorescence light was also demonstrated. The antiproliferative activity of the synthesized indolinones was evaluated against three human cancer cell lines.",

author = "Cheng, {Li Ting} and Luo, {Sheng Qi} and Hong, {Bor Cherng} and Chen, {Chia Ling} and Li, {Wen Shan} and Lee, {Gene Hsiang}",

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T1 - Oxidative trimerization of indoles via water-assisted visible-light photoredox catalysis and the study of their anti-cancer activities

AU - Cheng, Li Ting

AU - Luo, Sheng Qi

AU - Hong, Bor Cherng

AU - Chen, Chia Ling

AU - Li, Wen Shan

AU - Lee, Gene Hsiang

PY - 2020/8/28

Y1 - 2020/8/28

N2 - Incorporation of water has been revealed to successfully facilitate visible-light photoredox catalysis of indole leading to increased production of C2-quaternary indolinone. The water-promoted photoreaction of indole under catalyst-free conditions by a household compact fluorescence light was also demonstrated. The antiproliferative activity of the synthesized indolinones was evaluated against three human cancer cell lines.

AB - Incorporation of water has been revealed to successfully facilitate visible-light photoredox catalysis of indole leading to increased production of C2-quaternary indolinone. The water-promoted photoreaction of indole under catalyst-free conditions by a household compact fluorescence light was also demonstrated. The antiproliferative activity of the synthesized indolinones was evaluated against three human cancer cell lines.

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U2 - 10.1039/d0ob01298j

DO - 10.1039/d0ob01298j

M3 - 文章

C2 - 32735638

AN - SCOPUS:85089712909

SN - 1477-0520

VL - 18

SP - 6247

EP - 6252

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 32

ER -

Oxidative trimerization of indoles via water-assisted visible-light photoredox catalysis and the study of their anti-cancer activities

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