Pathogen recognition or homeostasis? APC receptor functions in innate immunity

Siamon Gordon

doi:10.1016/j.crvi.2004.04.005

Pathogen recognition or homeostasis? APC receptor functions in innate immunity

Siamon Gordon^*

^*此作品的通信作者

University of Oxford

研究成果: 期刊稿件 › 文章 › 同行評審

26 引文斯高帕斯（Scopus）

摘要

Myeloid cells (macrophages, neutrophils, dendritic cells) express a repertoire of plasma membrane receptors able to recognize all classes of macromolecules. The concept of pattern recognition has emphasized microbial ligands and host defence. However, these receptors play a broader role in tissue homeostasis within multicellular hosts, clearing the extracellular environment of potential undesirable ligands arising endogenously as well as from without. This article will evaluate one of the paradigms that underlie innate immunity.

原文	英語
頁（從 - 到）	603-607
頁數	5
期刊	Comptes Rendus - Biologies
卷	327
發行號	6
DOIs	https://doi.org/10.1016/j.crvi.2004.04.005
出版狀態	已出版 - 06 2004
對外發佈	是

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KW - Dendritic cells

KW - Lectins

KW - Macrophages

KW - Pathogens

KW - Receptors

KW - Scavenger receptors

UR - https://www.scopus.com/pages/publications/3242793342

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Pathogen recognition or homeostasis? APC receptor functions in innate immunity

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