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Plasma-treated and collagen-coated plla nanofiber membrane for cartilage tissue engineering

  • J. P. Chen*
  • , S. F. Lee
  • , I. P. Chiang
  • *此作品的通信作者
  • Chang Gung University

研究成果: 圖書/報告稿件的類型會議稿件同行評審

2 引文 斯高帕斯(Scopus)

摘要

Biodegradable nanofiber membranes from poly-L-lactic acid (PLLA) were prepared by electrospinning and used as a scaffold for cartilage tissue engineering. Operating parameters during the electrospinning process were studied in details in terms of fiber diameter and pore size of the membranes. The nanofiber membranes were characterized by SEM, FESEM, BET, AFM, and TEM. In order to improve cell attachment and growth, nanofibers were subjected to DC-pulsed oxygen plasma treatment, acrylic acid grafting, and collagen coating by covalent binding of collagen to carboxylic moieties of the polyacrylic acid. The bioactive scaffolds could be used for culture of chondrocyte with improved cell viability, proliferation, and differentiation.

原文英語
主出版物標題2005 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2005 Technical Proceedings
編輯M. Laudon, B. Romanowicz
頁面100-103
頁數4
出版狀態已出版 - 2005
事件2005 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2005 - Anaheim, CA, 美國
持續時間: 08 05 200512 05 2005

出版系列

名字2005 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2005 Technical Proceedings

Conference

Conference2005 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2005
國家/地區美國
城市Anaheim, CA
期間08/05/0512/05/05

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