Postreplicational formation and repair of DNA double-strand breaks in UV-irradiated Escherichia coli uvrB cells

Tzu chien V. Wang; Kendric C. Smith

doi:10.1016/0167-8817(86)90007-6

Postreplicational formation and repair of DNA double-strand breaks in UV-irradiated Escherichia coli uvrB cells

Tzu chien V. Wang^*
, Kendric C. Smith

^*此作品的通信作者

Stanford University

研究成果: 期刊稿件 › 文章 › 同行評審

51 引文斯高帕斯（Scopus）

摘要

The number of DNA double-strand breaks formed in UV-irradiated uvrB rec F recB cells correlates with the number of unrepaired DNA daughter-strand gaps, and is dependent on DNA synthesis after UV-irradiation. These results are consistent with the model that the DNA double-strand breaks that are produced in UV-irradiated excision-deficient cells occur as the results of breaks in the parental DNA opposite unrepaired DNA daughter-strand gaps. By employing a temperature-sensitive recA200 mutation, breaks. Possible mechanisms for the postreplication repair of DNA double-strand breaks are discussed.

原文	英語
頁（從 - 到）	39-44
頁數	6
期刊	Mutation Research DNA Repair Reports
卷	165
發行號	1
DOIs	https://doi.org/10.1016/0167-8817(86)90007-6
出版狀態	已出版 - 01 1986
對外發佈	是

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10.1016/0167-8817(86)90007-6

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title = "Postreplicational formation and repair of DNA double-strand breaks in UV-irradiated Escherichia coli uvrB cells",

abstract = "The number of DNA double-strand breaks formed in UV-irradiated uvrB rec F recB cells correlates with the number of unrepaired DNA daughter-strand gaps, and is dependent on DNA synthesis after UV-irradiation. These results are consistent with the model that the DNA double-strand breaks that are produced in UV-irradiated excision-deficient cells occur as the results of breaks in the parental DNA opposite unrepaired DNA daughter-strand gaps. By employing a temperature-sensitive recA200 mutation, breaks. Possible mechanisms for the postreplication repair of DNA double-strand breaks are discussed.",

author = "Wang, \{Tzu chien V.\} and Smith, \{Kendric C.\}",

year = "1986",

month = jan,

doi = "10.1016/0167-8817(86)90007-6",

language = "英语",

volume = "165",

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T1 - Postreplicational formation and repair of DNA double-strand breaks in UV-irradiated Escherichia coli uvrB cells

AU - Wang, Tzu chien V.

AU - Smith, Kendric C.

PY - 1986/1

Y1 - 1986/1

N2 - The number of DNA double-strand breaks formed in UV-irradiated uvrB rec F recB cells correlates with the number of unrepaired DNA daughter-strand gaps, and is dependent on DNA synthesis after UV-irradiation. These results are consistent with the model that the DNA double-strand breaks that are produced in UV-irradiated excision-deficient cells occur as the results of breaks in the parental DNA opposite unrepaired DNA daughter-strand gaps. By employing a temperature-sensitive recA200 mutation, breaks. Possible mechanisms for the postreplication repair of DNA double-strand breaks are discussed.

AB - The number of DNA double-strand breaks formed in UV-irradiated uvrB rec F recB cells correlates with the number of unrepaired DNA daughter-strand gaps, and is dependent on DNA synthesis after UV-irradiation. These results are consistent with the model that the DNA double-strand breaks that are produced in UV-irradiated excision-deficient cells occur as the results of breaks in the parental DNA opposite unrepaired DNA daughter-strand gaps. By employing a temperature-sensitive recA200 mutation, breaks. Possible mechanisms for the postreplication repair of DNA double-strand breaks are discussed.

UR - https://www.scopus.com/pages/publications/1542674947

U2 - 10.1016/0167-8817(86)90007-6

DO - 10.1016/0167-8817(86)90007-6

M3 - 文章

C2 - 3510373

AN - SCOPUS:1542674947

SN - 0167-8817

VL - 165

SP - 39

EP - 44

JO - Mutation Research DNA Repair Reports

JF - Mutation Research DNA Repair Reports

IS - 1

ER -

Postreplicational formation and repair of DNA double-strand breaks in UV-irradiated Escherichia coli uvrB cells

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